Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin

Gliotoxin, and other related molecules, are encoded by multi-gene clusters and biosynthesized by fungi using non-ribosomal biosynthetic mechanisms. Almost universally described in terms of its toxicity towards mammalian cells, gliotoxin has come to be considered as a component of the virulence arsen...

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Veröffentlicht in:PLoS pathogens 2010-06, Vol.6 (6), p.e1000952
Hauptverfasser: Schrettl, Markus, Carberry, Stephen, Kavanagh, Kevin, Haas, Hubertus, Jones, Gary W, O'Brien, Jennifer, Nolan, Aine, Stephens, John, Fenelon, Orla, Doyle, Sean
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Sprache:eng
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