Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals

In the past few decades, consumption of added sugars has increased dramatically. Studies have linked high sugar intake with increased risk for a number of diseases. Importantly, fructose, a component of sugar, has been linked with the development of features of metabolic syndrome. This study determi...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e52062-e52062
Hauptverfasser:	Le, MyPhuong T, Lobmeyer, Maximilian T, Campbell, Marcus, Cheng, Jing, Wang, Zhiying, Turner, Stephen T, Chapman, Arlene B, Boerwinkle, Eric, Gums, John G, Gong, Yan, Johnson, Richard J, Johnson, Julie A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids African Americans African Americans - genetics Antihypertensives Biology Blood lipids Blood pressure Cardiovascular disease Cardiovascular diseases Cholesterol Chromosomes Demography Density Development and progression Diabetes Drug therapy Epidemiology European Continental Ancestry Group - genetics Female Fructokinases - genetics Fructose Genes Genetic aspects Genetic Predisposition to Disease Genomes Glucose Glucose transporter Glucose Transporter Type 2 - genetics Glucose Transporter Type 5 - genetics Health risks Humans Hypertension Hypertension - blood Hypertension - genetics Hypertension - metabolism Insulin Ketohexokinase Kidney diseases Lipoproteins Low density lipoprotein Male Males Medical research Medicine Metabolic disorders Metabolic syndrome Metabolism Middle Aged Minority & ethnic groups Pharmacogenomics Pharmacology Pharmacy Phenotype Phenotypes Polymorphism Polymorphism, Single Nucleotide - genetics Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Sugar Type 2 diabetes Uric acid Uric Acid - blood
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