Pathogen induced changes in the protein profile of human tears from Fusarium keratitis patients

Fusarium is the major causative agent of fungal infections leading to corneal ulcer (keratitis) in Southern India and other tropical countries. Keratitis caused by Fusarium is a difficult disease to treat unless antifungal therapy is initiated during the early stages of infection. In this study tear...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e53018-e53018
Hauptverfasser:	Ananthi, Sivagnanam, Venkatesh Prajna, Namperumalsamy, Lalitha, Prajna, Valarnila, Murugesan, Dharmalingam, Kuppamuthu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albumin Analysis Antifungal agents Apolipoproteins Aspergillus Biochemistry Biology Chains Cornea Cystatin Cystatins Data processing Diabetic retinopathy Electrophoresis, Gel, Two-Dimensional Eye Proteins - genetics Eye Proteins - metabolism Female Fungi Fungicides Fusariosis - genetics Fusariosis - metabolism Fusariosis - microbiology Fusarium Fusarium - isolation & purification Fusarium - physiology Gel electrophoresis Gene Expression Regulation Glycoproteins Glycoproteins - genetics Glycoproteins - metabolism Haptoglobin Haptoglobins - genetics Haptoglobins - metabolism Health aspects Histology Host-Pathogen Interactions Humans Infection Infections Keratitis Keratitis - genetics Keratitis - metabolism Keratitis - microbiology Lactoferrin Lipocalin Lipocalins - genetics Lipocalins - metabolism Male Mass Spectrometry Mass spectroscopy Medical research Medicine Middle Aged Mycoses Patients Proteins Proteomics Tearing Tears Tears - metabolism Tears - microbiology Ulcers Young Adult Zinc
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