A structural-based strategy for recognition of transcription factor binding sites

Scanning through genomes for potential transcription factor binding sites (TFBSs) is becoming increasingly important in this post-genomic era. The position weight matrix (PWM) is the standard representation of TFBSs utilized when scanning through sequences for potential binding sites. However, many...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e52460-e52460
Hauptverfasser:	Xu, Beisi, Schones, Dustin E, Wang, Yongmei, Liang, Haojun, Li, Guohui
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Binding Sites Biochemistry Bioinformatics Biology Computer Science Databases, Protein Deoxyribonucleic acid DNA DNA methylation DNA structure DNA, Fungal - chemistry DNA, Fungal - genetics DNA, Fungal - metabolism Energy Energy consumption Gene expression Genomes Genomics Information processing Knowledge Knowledge Bases Laboratories Models, Molecular Molecular biology Nucleic Acid Conformation Position-Specific Scoring Matrices Predictions Protein Conformation Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Scanning Science Transcription factors Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors - metabolism
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