Pandemic vaccine preparedness--have we left something behind?

  Since 1997, most scientific studies have focused on avian H5, and to a minor extent avian H7 and H9 subtype viruses, because these viruses have caused repeated zoonotic human infections and have spread widely in poultry over the past 10 years or more. There are significant antigenic differences wi...

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Veröffentlicht in:PLoS pathogens 2009-06, Vol.5 (6), p.e1000482-e1000482
Hauptverfasser: Capua, Ilaria, Kajaste-Rudnitski, Anna, Bertoli, Elena, Vicenzi, Elisa
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creator Capua, Ilaria
Kajaste-Rudnitski, Anna
Bertoli, Elena
Vicenzi, Elisa
description   Since 1997, most scientific studies have focused on avian H5, and to a minor extent avian H7 and H9 subtype viruses, because these viruses have caused repeated zoonotic human infections and have spread widely in poultry over the past 10 years or more. There are significant antigenic differences within subtypes that change over time as these viruses evolve, and this requires a semi-annual review and frequent update of vaccine strain candidates for human seasonal influenza vaccines.
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subjects Adult
Animals
Antigens, Viral - immunology
Birds
Causes of
Disaster Planning
Disease Outbreaks - prevention & control
Emergency management
Health aspects
Hemagglutination Inhibition Tests
Humans
Immunization
Influenza
Influenza A virus - immunology
Influenza A Virus, H1N1 Subtype - immunology
Influenza A Virus, H2N2 Subtype - immunology
Influenza A Virus, H3N2 Subtype - immunology
Influenza in Birds - virology
Influenza vaccines
Influenza Vaccines - administration & dosage
Influenza Vaccines - immunology
Influenza, Human - prevention & control
Influenza, Human - virology
Methods
Middle Aged
Opinion
Pandemics
Prevention
Public health
Vaccines
Virology
Virology/Immune Evasion
Virology/Vaccines
title Pandemic vaccine preparedness--have we left something behind?
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