The Ebola virus VP35 protein is a suppressor of RNA silencing

RNA silencing or interference (RNAi) is a gene regulation mechanism in eukaryotes that controls cell differentiation and developmental processes via expression of microRNAs. RNAi also serves as an innate antiviral defence response in plants, nematodes, and insects. This antiviral response is trigger...

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Veröffentlicht in:	PLoS pathogens 2007-06, Vol.3 (6), p.e86-e86
Hauptverfasser:	Haasnoot, J, Vries, W. de, Geutjes, E.J, Prins, M.W, Haan, P. de, Berkhout, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antiviral defense Base Sequence caenorhabditis-elegans Cell Biology Cercopithecus aethiops double-stranded-rna Ebola virus Eukaryotes Gene Products, tat - physiology Genetic aspects hepatitis-c virus HIV-1 - physiology Homo (Human) human-immunodeficiency-virus Humans Immune system Immunity, Innate Immunology Infectious Diseases Influence influenza-a virus Interferons - antagonists & inhibitors Kinases Molecular Sequence Data ns1 protein Nucleoproteins - physiology Proteins Ribonucleic acid RNA RNA Interference RNA, Double-Stranded - metabolism RNA-Binding Proteins - physiology small interfering rnas tat Gene Products, Human Immunodeficiency Virus Transcriptional Activation type-1 replication vaccinia virus Vero Cells Viral Core Proteins - physiology Viral Nonstructural Proteins - physiology Viral proteins Viral Proteins - physiology Virology Virus Diseases - immunology Virus Replication Viruses
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