Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

Analysis of mycobacterial strains that have lost their ability to cause disease is a powerful approach to identify yet unknown virulence determinants and pathways involved in tuberculosis pathogenesis. Two of the most widely used attenuated strains in the history of tuberculosis research are Mycobac...

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Veröffentlicht in:	PLoS pathogens 2008-02, Vol.4 (2), p.e33-e33
Hauptverfasser:	Frigui, Wafa, Bottai, Daria, Majlessi, Laleh, Monot, Marc, Josselin, Emmanuelle, Brodin, Priscille, Garnier, Thierry, Gicquel, Brigitte, Martin, Carlos, Leclerc, Claude, Cole, Stewart T, Brosch, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Bacterial Antigens, Bacterial - genetics Antigens, Bacterial - immunology Antigens, Bacterial - metabolism Bacterial Proteins Bacterial Proteins - genetics Bacterial Proteins - immunology Bacterial Proteins - metabolism Biochemistry, Molecular Biology Cells, Cultured Disease Models, Animal DNA Mutational Analysis Eubacteria Gene Expression Regulation Genes Infectious Diseases Life Sciences Lymphocyte Activation Macrophages Macrophages - microbiology Male Mice Mice, SCID Microbiology Molecular Biology Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycobacterium tuberculosis - metabolism Mycobacterium tuberculosis - pathogenicity Oligonucleotide Array Sequence Analysis Spleen Spleen - cytology Spleen - immunology Studies T-Lymphocytes T-Lymphocytes - immunology Tuberculosis Virulence
Online-Zugang:	Volltext
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