Host-specific response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: role of the innate antiviral immune response

The severe combined immunodeficiency disorder (SCID)-beige/albumin (Alb)-urokinase plasminogen activator (uPA) mouse containing a human-mouse chimeric liver is currently the only small animal model capable of supporting hepatitis C virus (HCV) infection. This model was utilized to characterize the h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2006-06, Vol.2 (6), p.e59-e59
Hauptverfasser:	Walters, Kathie-Anne, Joyce, Michael A, Thompson, Jill C, Smith, Maria W, Yeh, Matthew M, Proll, Sean, Zhu, Lin-Fu, Gao, T J, Kneteman, Norman M, Tyrrell, D Lorne, Katze, Michael G
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins Animal models Animals Antibodies, Viral - biosynthesis Bioinformatics - Computational Biology Chimera Gastroenterology - Hepatology Gene expression Gene Expression Profiling Genetic aspects Hepatitis Hepatitis C Hepatitis C - genetics Hepatitis C - immunology Hepatitis C - metabolism Hepatocytes - transplantation Host-virus relationships Humans Immune response Immunity, Innate Infections Lipid Metabolism Liver - metabolism Medical research Mice Mice, SCID - genetics Mice, SCID - immunology Mus (Mouse) Oxidative Stress Physiological aspects Proteins Rodents Signal Transduction - immunology Urokinase-Type Plasminogen Activator - genetics Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!