Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection

The efficient clearance of microbes by neutrophils requires the concerted action of reactive oxygen species and microbicidal components within leukocyte secretory granules. Rubrerythrin (Rbr) is a nonheme iron protein that protects many air-sensitive bacteria against oxidative stress. Using oxidativ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2006-07, Vol.2 (7), p.e76-e76
Hauptverfasser:	Mydel, Piotr, Takahashi, Yusuke, Yumoto, Hiromichi, Sztukowska, Maryta, Kubica, Malgorzata, Gibson, 3rd, Frank C, Kurtz, Jr, Donald M, Travis, Jim, Collins, L Vincent, Nguyen, Ky-Anh, Genco, Caroline Attardo, Potempa, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaerobic infection Animals Antioxidants - metabolism Bacteria Bacterial Proteins - genetics Bacterial Proteins - immunology Bacteroidaceae Infections - genetics Bacteroidaceae Infections - immunology Bacteroidaceae Infections - metabolism bacteroides-gingivalis Biological Sciences Biologiska vetenskaper burkholderia-cepacia chronic granulomatous-disease Disease Disease Models, Animal Female Ferredoxins - deficiency Ferredoxins - genetics Ferredoxins - immunology Flow cytometry Gingivitis Gum diseases Hemerythrin Humans hydrogen-peroxide Immunity, Mucosal - genetics Immunity, Mucosal - immunology In vivo Infections Infectious Diseases Infectious Medicine Infektionsmedicin Inflammation Mice Mice, Inbred C57BL Mice, Knockout Microbiology Microbiology in the medical area Mikrobiologi inom det medicinska området Mortality NADPH oxidase NADPH Oxidases - deficiency NADPH Oxidases - genetics neutrophil activation Neutrophils - immunology Neutrophils - metabolism Nitric oxide nitric-oxide synthase Nitrogen Oxidative stress Oxidative Stress - genetics Oxidative Stress - immunology Pathology Peptides periodontal bacteria phagocytic-cells Physiological aspects polymorphonuclear leukocytes Porphyromonas gingivalis Porphyromonas gingivalis - genetics Porphyromonas gingivalis - immunology Porphyromonas gingivalis - metabolism Prevention Proteins Respiratory Burst - genetics Respiratory Burst - immunology ROS Rubredoxins virulence
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!