The genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide

Lipopolysaccharide (LPS) is one of the most important virulence and antigenic components of Burkholderia pseudomallei, the causative agent of melioidosis. LPS diversity in B. pseudomallei has been described as typical, atypical or rough, based upon banding patterns on SDS-PAGE. Here, we studied the...

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Veröffentlicht in:	PLoS neglected tropical diseases 2012-01, Vol.6 (1), p.e1453
Hauptverfasser:	Tuanyok, Apichai, Stone, Joshua K, Mayo, Mark, Kaestli, Mirjam, Gruendike, Jeffrey, Georgia, Shalamar, Warrington, Stephanie, Mullins, Travis, Allender, Christopher J, Wagner, David M, Chantratita, Narisara, Peacock, Sharon J, Currie, Bart J, Keim, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigenic Variation - genetics Antigenic Variation - immunology Asia, Southeastern Australia Bacteriology Bioinformatics Biology Biosynthesis Burkholderia pseudomallei Burkholderia pseudomallei - genetics Burkholderia pseudomallei - immunology Burkholderia pseudomallei - isolation & purification Causes of Computational Biology DNA, Bacterial - chemistry DNA, Bacterial - genetics Gene mutations Genes Genetic aspects Genotype Genotypes Health aspects Humans Immune response Lipopolysaccharides - genetics Lipopolysaccharides - immunology Medicine Melioidosis - microbiology Microbiology Molecular Sequence Data Mortality Multiplex Polymerase Chain Reaction - methods Mutation O Antigens - genetics O Antigens - immunology Physiological aspects Pseudomonas infections Sequence Alignment Sequence Analysis, DNA Sequence Homology, Nucleic Acid Tropical diseases
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