Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice--the liver and spleen being mainly studied-or in vitro. Whatever stationary phase L. infantum promastigotes population--wild t...

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Veröffentlicht in:PLoS neglected tropical diseases 2011-09, Vol.5 (9), p.e1323-e1323
Hauptverfasser: Michel, Grégory, Ferrua, Bernard, Lang, Thierry, Maddugoda, Madhavi P, Munro, Patrick, Pomares, Christelle, Lemichez, Emmanuel, Marty, Pierre
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Sprache:eng
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