Therapeutic DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis

Paracoccidioidomycosis (PCM), caused by Paracoccidioides brasiliensis, is the most prevalent invasive fungal disease in South America. Systemic mycoses are the 10th most common cause of death among infectious diseases in Brazil and PCM is responsible for more than 50% of deaths due to fungal infecti...

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Veröffentlicht in:	PLoS neglected tropical diseases 2012-02, Vol.6 (2), p.e1519-e1519
Hauptverfasser:	Rittner, Glauce M G, Muñoz, Julián E, Marques, Alexandre F, Nosanchuk, Joshua D, Taborda, Carlos P, Travassos, Luiz R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Fungal - immunology Biology Colony Count, Microbial Disease Models, Animal DNA vaccines Dosage and administration Fungal Vaccines - administration & dosage Fungal Vaccines - immunology Genetic aspects Genetic code Genetic Vectors Glycoproteins - immunology Immunotherapy - methods Injections, Intramuscular Lung - microbiology Lung - pathology Male Mice Mice, Inbred BALB C Paracoccidioides - immunology Paracoccidioidomycosis Paracoccidioidomycosis - immunology Paracoccidioidomycosis - therapy Peptide Fragments - immunology Plasmids Prevention Risk factors Vaccines, DNA - administration & dosage Vaccines, DNA - immunology
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