Effect of duration and intermittency of rifampin on tuberculosis treatment outcomes: a systematic review and meta-analysis

Treatment regimens for active tuberculosis (TB) that are intermittent, or use rifampin during only the initial phase, offer practical advantages, but their efficacy has been questioned. We conducted a systematic review of treatment regimens for active TB, to assess the effect of duration and intermi...

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Veröffentlicht in:	PLoS medicine 2009-09, Vol.6 (9), p.e1000146-e1000146
Hauptverfasser:	Menzies, Dick, Benedetti, Andrea, Paydar, Anita, Martin, Ian, Royce, Sarah, Pai, Madhukar, Vernon, Andrew, Lienhardt, Christian, Burman, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antitubercular - administration & dosage Antibiotics, Antitubercular - therapeutic use Clinical trials Drug Administration Schedule Drug resistance Drug Resistance, Bacterial Drug therapy Humans Infectious Diseases/Epidemiology and Control of Infectious Diseases Infectious Diseases/Neglected Tropical Diseases Isoniazid - therapeutic use Medical research Public Health and Epidemiology/Global Health Randomized Controlled Trials as Topic Recurrence Regression Analysis Rifampin - administration & dosage Rifampin - therapeutic use Risk Factors Streptomycin - therapeutic use Studies Treatment Failure Tuberculosis Tuberculosis, Pulmonary - drug therapy
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