Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya

Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or their soluble products, thereby stimulating T and B cell immune responses to malaria blood stage antigens. We hypothesized that fetal immune priming, or malaria exposure in the absence of priming (putative tolerance), affe...

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Veröffentlicht in:PLoS medicine 2009-07, Vol.6 (7), p.e1000116-e1000116
Hauptverfasser: Malhotra, Indu, Dent, Arlene, Mungai, Peter, Wamachi, Alex, Ouma, John H, Narum, David L, Muchiri, Eric, Tisch, Daniel J, King, Christopher L
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Sprache:eng
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