High-performance liquid chromatography method for the separation of isomers of 9β-methylcarbacyclin (ciprostene) and the analysis of pharmaceutical samples

An high-performance liquid chromatography method was developed that separates (5Z)-9 beta-methyl-6 alpha-carbaprostaglandin I2 (9 beta-methylcarbacyclin; ciprostene) from several closely related isomers: (i) a double bond isomer at C-5, (ii) an epimer at C-15, and (iii) combinations of i and ii. The...

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Veröffentlicht in:	Journal of chromatography 1985-03, Vol.321 (1), p.209-215
Hauptverfasser:	THEIS, D. L, RUSK, M. L, PLAISTED, S. M, SNIDER, B. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromatography, High Pressure Liquid Drug Stability Epoprostenol - analysis General pharmacology Indicators and Reagents Isomerism Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Spectrophotometry, Ultraviolet Temperature
Online-Zugang:	Volltext
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