High-performance liquid chromatographic determination of acid-catalyzed degradation products of methyl carboprost in a polymeric controlled-release device

A normal-phase high-performance liquid chromatographic method was used for the determination of methyl carboprost and acid-catalyzed degradation products in a polymer-based, controlled release dosage form. A reversed-phase method was used to isolate sufficient quantities of the degradation products...

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Veröffentlicht in:	Journal of chromatography 1984-11, Vol.314, p.369-377
Hauptverfasser:	PLAISTED, S. M, DEZWAAN, J, SNIDER, B. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carboprost - analysis Chemical Phenomena Chemistry Chromatography, High Pressure Liquid - methods Drug Stability General pharmacology Hydrogen-Ion Concentration Medical sciences Membranes, Artificial Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers Prostaglandins F, Synthetic - analysis
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