Production of Antibody Associated with non-A, non-B Hepatitis in a Chimpanzee Lymphoblastoid Cell Line Established by in vitro Transformation with Epstein-Barr Virus

A continuous cell line of chimpanzee lymphocytes producing an antibody specifically associated with non-A, non-B hepatitis (NANB) was established. Peripheral blood lymphocytes of a chimpanzee convalescent from experimental infection with NANB hepatitis were transformed in vitro by Epstein-Barr virus...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1985-04, Vol.82 (7), p.2138-2142
Hauptverfasser:	Shimizu, Yohko K., Oomura, Masashi, Abe, Kengi, Uno, Masatune, Yamada, Ei, Ono, Yasushi, Shikata, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Antibodies Antibodies, Viral - analysis Biological and medical sciences Biopsies Biotechnology Cell Line Cell Transformation, Viral Epstein Barr virus infections Epstein-Barr virus Establishment of new cell lines, improvement of cultural methods, mass cultures Eukaryotic cell cultures Fundamental and applied biological sciences. Psychology Hepatitis Hepatitis A Hepatitis C - immunology Hepatitis C - pathology Hepatitis, Viral, Human - immunology Hepatocytes Herpesvirus 4, Human Inoculation Liver Lymphocytes Lymphocytes - immunology Methods. Procedures. Technologies Microbiology Pan troglodytes Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Transformed cell line Virology
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