Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury
To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head-injured children and adolescents were studied at least 6 years after injury. Three-dimensional MR...
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| Veröffentlicht in: | Brain injury 2001-03, Vol.15 (3), p.211-221 |
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| creator | VERGER, K JUNQUE, C LEVIN, H. S JURADO, M. A PEREZ-GOMEZ, M BARTRES-FAZ, D BARRIOS, M ALVAREZ, A BARTUMEUS, F MERCADER, J. M |
| description | To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head-injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients. |
| doi_str_mv | 10.1080/02699050010004059 |
| format | Article |
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S ; JURADO, M. A ; PEREZ-GOMEZ, M ; BARTRES-FAZ, D ; BARRIOS, M ; ALVAREZ, A ; BARTUMEUS, F ; MERCADER, J. M</creator><creatorcontrib>VERGER, K ; JUNQUE, C ; LEVIN, H. S ; JURADO, M. A ; PEREZ-GOMEZ, M ; BARTRES-FAZ, D ; BARRIOS, M ; ALVAREZ, A ; BARTUMEUS, F ; MERCADER, J. M</creatorcontrib><description>To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head-injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients.</description><identifier>ISSN: 0269-9052</identifier><identifier>EISSN: 1362-301X</identifier><identifier>DOI: 10.1080/02699050010004059</identifier><identifier>PMID: 11260770</identifier><identifier>CODEN: BRAIEO</identifier><language>eng</language><publisher>London: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Atrophy ; Biological and medical sciences ; Brain - pathology ; Brain Damage, Chronic - diagnosis ; Brain Damage, Chronic - psychology ; Brain Injury, Chronic - diagnosis ; Brain Injury, Chronic - psychology ; Cerebral Ventricles - pathology ; Child ; Child, Preschool ; Corpus Callosum - pathology ; Female ; Follow-Up Studies ; Humans ; Image Processing, Computer-Assisted ; Injuries of the nervous system and the skull. Diseases due to physical agents ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Neuropsychological Tests ; Reference Values ; Traumas. Diseases due to physical agents</subject><ispartof>Brain injury, 2001-03, Vol.15 (3), p.211-221</ispartof><rights>2001 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2001</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c463t-6f71f98027a18e1d8311fc83178bd891af7408b35dbec5fabd446c610faa60a73</citedby><cites>FETCH-LOGICAL-c463t-6f71f98027a18e1d8311fc83178bd891af7408b35dbec5fabd446c610faa60a73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/02699050010004059$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/02699050010004059$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=913687$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11260770$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VERGER, K</creatorcontrib><creatorcontrib>JUNQUE, C</creatorcontrib><creatorcontrib>LEVIN, H. S</creatorcontrib><creatorcontrib>JURADO, M. A</creatorcontrib><creatorcontrib>PEREZ-GOMEZ, M</creatorcontrib><creatorcontrib>BARTRES-FAZ, D</creatorcontrib><creatorcontrib>BARRIOS, M</creatorcontrib><creatorcontrib>ALVAREZ, A</creatorcontrib><creatorcontrib>BARTUMEUS, F</creatorcontrib><creatorcontrib>MERCADER, J. M</creatorcontrib><title>Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury</title><title>Brain injury</title><addtitle>Brain Inj</addtitle><description>To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head-injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Atrophy</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Brain Damage, Chronic - diagnosis</subject><subject>Brain Damage, Chronic - psychology</subject><subject>Brain Injury, Chronic - diagnosis</subject><subject>Brain Injury, Chronic - psychology</subject><subject>Cerebral Ventricles - pathology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Corpus Callosum - pathology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Injuries of the nervous system and the skull. Diseases due to physical agents</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neuropsychological Tests</subject><subject>Reference Values</subject><subject>Traumas. 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M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury</atitle><jtitle>Brain injury</jtitle><addtitle>Brain Inj</addtitle><date>2001-03-01</date><risdate>2001</risdate><volume>15</volume><issue>3</issue><spage>211</spage><epage>221</epage><pages>211-221</pages><issn>0269-9052</issn><eissn>1362-301X</eissn><coden>BRAIEO</coden><abstract>To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head-injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients.</abstract><cop>London</cop><pub>Informa UK Ltd</pub><pmid>11260770</pmid><doi>10.1080/02699050010004059</doi><tpages>11</tpages></addata></record> |
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| subjects | Adolescent Adult Atrophy Biological and medical sciences Brain - pathology Brain Damage, Chronic - diagnosis Brain Damage, Chronic - psychology Brain Injury, Chronic - diagnosis Brain Injury, Chronic - psychology Cerebral Ventricles - pathology Child Child, Preschool Corpus Callosum - pathology Female Follow-Up Studies Humans Image Processing, Computer-Assisted Injuries of the nervous system and the skull. Diseases due to physical agents Magnetic Resonance Imaging Male Medical sciences Neuropsychological Tests Reference Values Traumas. Diseases due to physical agents |
| title | Correlation of atrophy measures on MRI with neuropsychological sequelae in children and adolescents with traumatic brain injury |
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