Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging
A method is described for determining the spatial distribution of radiation dose in a tissue-equivalent phantom using nuclear magnetic resonance imaging. The conversion of ferrous ions to ferric by ionising radiation alters the magnetic moment and electron spin relaxation times of the metal ion. The...
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Veröffentlicht in: | Physics in medicine & biology 1984-10, Vol.29 (10), p.1189-1197 |
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creator | Gore, J C Kang, Y S |
description | A method is described for determining the spatial distribution of radiation dose in a tissue-equivalent phantom using nuclear magnetic resonance imaging. The conversion of ferrous ions to ferric by ionising radiation alters the magnetic moment and electron spin relaxation times of the metal ion. The spin relaxation times (T1 and T2) of the hydrogen nuclei in an aqueous solution of a ferrous salt are consequently reduced substantially. These changes in T1 and T2 can be measured using standard NMR techniques. The same conversion is used in conventional Fricke dosimetry, which can be used to calibrate the technique. |
doi_str_mv | 10.1088/0031-9155/29/10/002 |
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The conversion of ferrous ions to ferric by ionising radiation alters the magnetic moment and electron spin relaxation times of the metal ion. The spin relaxation times (T1 and T2) of the hydrogen nuclei in an aqueous solution of a ferrous salt are consequently reduced substantially. These changes in T1 and T2 can be measured using standard NMR techniques. The same conversion is used in conventional Fricke dosimetry, which can be used to calibrate the technique.</description><identifier>ISSN: 0031-9155</identifier><identifier>EISSN: 1361-6560</identifier><identifier>DOI: 10.1088/0031-9155/29/10/002</identifier><identifier>PMID: 6494247</identifier><identifier>CODEN: PHMBA7</identifier><language>eng</language><publisher>Bristol: IOP Publishing</publisher><subject>Applied radiobiology (equipment, dosimetry...) ; Biological and medical sciences ; Biological effects of radiation ; Fundamental and applied biological sciences. 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The conversion of ferrous ions to ferric by ionising radiation alters the magnetic moment and electron spin relaxation times of the metal ion. The spin relaxation times (T1 and T2) of the hydrogen nuclei in an aqueous solution of a ferrous salt are consequently reduced substantially. These changes in T1 and T2 can be measured using standard NMR techniques. The same conversion is used in conventional Fricke dosimetry, which can be used to calibrate the technique.</description><subject>Applied radiobiology (equipment, dosimetry...)</subject><subject>Biological and medical sciences</subject><subject>Biological effects of radiation</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Magnetic Resonance Spectroscopy - methods</subject><subject>Models, Anatomic</subject><subject>Radiation Dosage</subject><subject>Tissues, organs and organisms biophysics</subject><issn>0031-9155</issn><issn>1361-6560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1LxDAQhoMoun78AhFyEFGh7qRN0_Yo4hfsKojiMSTpRCLddk3ag__elF32ogcPIWTeZ2bCQ8gxgysGZTkFyFhSsTyfptWUQXynW2TCMsESkQvYJpMNsUf2Q_gEYKxM-S7ZFbziKS8m5H2OKgweF9j2tLPUq9qp3nUtrbuAtHah904PYyVQ_U3bwTSoPF2ojxZ7Z6jH0LWqNUjPn-YvF9TFxLUfh2THqibg0fo-IG93t683D8ns-f7x5nqWmBygTzRW3AoQyGsQFnhuCgaKWZ7XWmHGRaWVFmhEPKBFwRjPtC6MMLVNQZfZATlbzV367mvA0MuFCwabRrXYDUEynkKZFSKC2Qo0vgvBo5VLH__qvyUDOeqUoyw5ypJpNRajzth1sh4_6AXWm561v5ifrnMVjGqsjyZc2GBlFTdXELGrFea65T_3Xv5u-AOUy9pmP9RPmA0</recordid><startdate>198410</startdate><enddate>198410</enddate><creator>Gore, J C</creator><creator>Kang, Y S</creator><general>IOP Publishing</general><general>Institute of Physics</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>198410</creationdate><title>Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging</title><author>Gore, J C ; Kang, Y S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-be94f606e4d06f045c710a1f45dbae3469bab6ec66ec0b671143bb7c6cdf20b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Applied radiobiology (equipment, dosimetry...)</topic><topic>Biological and medical sciences</topic><topic>Biological effects of radiation</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Magnetic Resonance Spectroscopy - methods</topic><topic>Models, Anatomic</topic><topic>Radiation Dosage</topic><topic>Tissues, organs and organisms biophysics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gore, J C</creatorcontrib><creatorcontrib>Kang, Y S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Physics in medicine & biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gore, J C</au><au>Kang, Y S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging</atitle><jtitle>Physics in medicine & biology</jtitle><addtitle>Phys Med Biol</addtitle><date>1984-10</date><risdate>1984</risdate><volume>29</volume><issue>10</issue><spage>1189</spage><epage>1197</epage><pages>1189-1197</pages><issn>0031-9155</issn><eissn>1361-6560</eissn><coden>PHMBA7</coden><abstract>A method is described for determining the spatial distribution of radiation dose in a tissue-equivalent phantom using nuclear magnetic resonance imaging. 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subjects | Applied radiobiology (equipment, dosimetry...) Biological and medical sciences Biological effects of radiation Fundamental and applied biological sciences. Psychology Humans Magnetic Resonance Spectroscopy - methods Models, Anatomic Radiation Dosage Tissues, organs and organisms biophysics |
title | Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging |
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