Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli

Purpose : 5-Formyluracil (5-foU) is a major derivative of thymine produced in DNA by ionizing radiation and various chemical oxidants. It has been previously shown that 5-foU in template DNA directs misincorporation of nucleotides by DNA polymerases during in vitro DNA synthesis. The present experim...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of radiation biology 2001, Vol.77 (1), p.53-58
1. Verfasser:	Miyabe, Q.-M. Zhang, H. Sugiyama, K. Kino, S. Yonei, I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes DNA - drug effects DNA Mutational Analysis Escherichia coli - metabolism Fundamental and applied biological sciences. Psychology Molecular and cellular biology Mutagenesis Mutation NADH, NADPH Oxidoreductases - genetics Plasmids - metabolism Uracil - adverse effects Uracil - analogs & derivatives Uracil - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!