Host Cell-Mediated Selection of a Mutant Influenza A Virus That Has Lost a Complex Oligosaccharide from the Tip of the Hemagglutinin

During serial passage in Madin-Darby bovine kidney (MDBK) cells, a substrain of influenza virus A/WSN is lost from the population and is replaced by a mutant virus with altered host cell binding properties. This selection does not occur during growth in chicken embryo fibroblasts (CEF). It occurs du...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1986-06, Vol.83 (11), p.3771-3775
Hauptverfasser:	Deom, Carl M., Caton, Andrew J., Schulze, Irene T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animals Base Sequence Biological and medical sciences Carbohydrates Cell growth Cell Line Cellular receptors Chromatography, Affinity Dogs Fundamental and applied biological sciences. Psychology Genes, Viral Genetic mutation Genetics Glycopeptides Glycoproteins - genetics Hemagglutinins, Viral - genetics Hexosaminidases - metabolism Influenza A virus - genetics Kidney Lectins - metabolism Microbiology Mutation Oligosaccharides Protein Processing, Post-Translational Receptors Receptors, Virus - metabolism Selection, Genetic Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!