Aγ‐haplotypes: A new group of genetic markers for thalassemic mutations inside the 5′ regulatory region of the human Aγ‐globin gene

This study illustrates the relationship between a group of nucleotide variations within the 5′ regulatory region of the Aγ‐globin gene [Aγ‐588 A→G, Aγ‐499 T→A and the 4‐bp deletion (Aγ‐225 to ‐222 AGCA)] and the spectrum of δ‐ and β‐thalassemia mutations in the Hellenic population. These sequence va...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of hematology 2001-02, Vol.66 (2), p.99-104
Hauptverfasser:	Patrinos, George P., Kollia, Panagoula, Papapanagiotou, Elisavet, Loutradi‐Anagnostou, Aphrodite, Loukopoulos, Dimitris, Papadakis, Manoussos N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemias. Hemoglobinopathies Biological and medical sciences DGGE Diseases of red blood cells haplotypes Hematologic and hematopoietic diseases Medical sciences mutations polymorphisms thalassemia γ‐globin genes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!