Metabolic oxidation of the pyrrole ring: structure and origin of some urinary metabolites of the anti-hypertensive pyrrolylpyridazinamine, mopidralazine.: III: Studies with the 13C-labelled drug

Abstract 1. The metabolism of the anti-hypertensive drug, mopidralazine, N-(2′,5′ -dimethyl-1H-pyrrol-1-yl)-6-(4″-morpholinyl)-3-pyridazinamine, was reinvestigated in rats using the [2′(5′)-CH3]-labelled drug to determine the significance of the pharmacologically active intermediate 3-hydrazino-6-(4...

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