Band-spacing in reversed-phase high-performance liquid chromatography as a function of solvent strength: A simple and fast alternative to solvent optimization for method development

Numerous reports have described the use of solvent optimization for isocratic reversed-phase high-performance liquid chromatography method development. Solvent optimization involves the use of different solvents (usually methanol, acetonitrile and tetrahydrofuran) to control band-spacing for maximum...

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Veröffentlicht in:	Journal of Chromatography A 1987-01, Vol.384, p.163-180
Hauptverfasser:	Quarry, M.A., Grob, R.L., Snyder, L.R., Dolan, J.W., Rigney, M.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Chromatographic methods and physical methods associated with chromatography Exact sciences and technology Other chromatographic methods
Online-Zugang:	Volltext
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