Effects of the myocardial‐selective α1‐adrenoceptor antagonist UK‐52046 and atenolol, alone and in combination, on experimental cardiac arrhythmias in dogs

1 Adrenaline‐induced arrhythmias in anaesthetized dogs respired with halothane were attenuated in 3 groups of 6 dogs by either UK‐52046, 3.8 ± 1.4μgkg−1 (mean ± s.e.mean), atenolol 14.6 ± 2.1 μgkg−1, or a combination containing equal amounts of the two drugs of 0.36 ± 0.1 μgkg−1. The pressor respons...

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Veröffentlicht in:	British journal of pharmacology 1988-12, Vol.95 (4), p.1241-1254
Hauptverfasser:	Uprichard, Andrew G.C., Harron, Dean W.G., Wilson, Richard, Shanks, Robin G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiarythmic agents Biological and medical sciences Cardiovascular system Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
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