Antioxidant Activities of Some Tryptophan Metabolites: Possible Implication for Inflammatory Diseases

The antioxidant properties of tryptophan and some of its oxidative metabolites were examined by measuring how efficiently they inhibited peroxyl radical-mediated oxidation of phosphatidylcholine liposomes and B-phycoerythrin. Low micromolar concentrations of 5-hydroxytryptophan, 3-hydroxykynurenine,...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1990-04, Vol.87 (7), p.2506-2510
Hauptverfasser:	Christen, Stephan, Peterhans, Ernst, Stocker, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoacids, peptides. Hormones. Neuropeptides Analytical, structural and metabolic biochemistry Animals Antioxidants Biological and medical sciences Enzymes Female Free Radicals Fundamental and applied biological sciences. Psychology Infections Inflammation - physiopathology Kinetics Kynurenine - metabolism Liposomes Lung - drug effects Lung - metabolism Lungs Metabolites Mice Mice, Inbred ICR Orthomyxoviridae Infections - physiopathology Oxidation Oxidative stress Peroxides - metabolism Proteins Reactive oxygen species Superoxides Tryptophan - analogs & derivatives Tryptophan - metabolism Tryptophan - pharmacology
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