Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier

Transport, binding, and metabolism of [phenylalanyl-3,4,5,-3H(N)]arginine vasopressin (AVP) by the blood-brain barrier (BBB) was studied in adult guinea-pigs by means of a novel vascular brain perfusion (VBP)/capillary depletion technique and HPLC. A time-dependent, progressive brain uptake of 3H-ra...

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Veröffentlicht in:	Brain research 1992-09, Vol.590 (1-2), p.213-218
Hauptverfasser:	ZLOKOVIC, B. V, BANKS, W. A, HIKMAT EL KADI, ERCHEGYI, J, MACKIC, J. B, MCCOMB, J. G, KASTIN, A. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine Vasopressin - blood Arginine Vasopressin - pharmacokinetics Biological and medical sciences Biological Transport - physiology Blood-Brain Barrier - physiology Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Chromatography, High Pressure Liquid Female Fundamental and applied biological sciences. Psychology Guinea Pigs Male Perfusion Protein Binding Scintillation Counting Vertebrates: nervous system and sense organs
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