PHASE-II STUDY - TREATMENT OF NON-HODGKINS-LYMPHOMA WITH AN ORAL ANTITUMOR DERIVATIVE OF BIS(2,6-DIOXOPIPERAZINE)

Background: Although razoxane (ICRF-159), a derivative of bis(2,6-dioxopiperazine), has shown significant antitumor activity in several murine tumors, inadequate bioavailability has limited its clinical efficacy. Sobuzoxane (MST-16), another derivative of bis(2,6-dioxopiperazine), has shown activity...

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Veröffentlicht in:JNCI : Journal of the National Cancer Institute 1992-03, Vol.84 (6), p.435-438
Hauptverfasser: OHNO, R, YAMADA, K, HIRANO, M, SHIRAKAWA, S, TANAKA, M, OGURI, T, KODERA, Y, MITOMO, Y, IKEDA, Y, YOKOMAKU, S, KAMIYA, O, KOBAYASHI, M, SAITO, H, KIMURA, K
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Sprache:eng
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