Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase

Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of medicinal chemistry 1992, Vol.35 (12), p.2315-2320
Hauptverfasser: DENNY, B. J, RINGAN, N. S, SCHWALBE, C. H, LAMBERT, P. A, MEEK, M. A, GRIFFIN, R. J, STEVENS, M. F. G
Format: Artikel
Sprache:eng
Schlagworte:
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Enzymes and enzyme inhibitors
Fundamental and applied biological sciences. Psychology
Oxidoreductases
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 2320
container_issue 12
container_start_page 2315
container_title Journal of medicinal chemistry
container_volume 35
creator DENNY, B. J
RINGAN, N. S
SCHWALBE, C. H
LAMBERT, P. A
MEEK, M. A
GRIFFIN, R. J
STEVENS, M. F. G
description
format Article
fullrecord <record><control><sourceid>pascalfrancis</sourceid><recordid>TN_cdi_pascalfrancis_primary_5405219</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>5405219</sourcerecordid><originalsourceid>FETCH-pascalfrancis_primary_54052193</originalsourceid><addsrcrecordid>eNqNjrtOxDAQAC0EEsfjH7agJMhxEgS0CERDBcV1p429uSxyvNHaQQp_w58CEgUl1TSj0RyYTd05W7U3tj00G2udq9y1a47NSc5v1tqmds3GfL4UXXxZFCPksgSmDJKgZ6nQF34n8DLNsqSQr2C7vYNnieSXiAqTBIqc9oApgNc1F4xR9orzyP5vbKIyrrGn9CGz8nQJCLMUSgU4jdxzEQUZIPC4BpVBIhYCpfD9hZnOzNGAMdP5L0_NxePD6_1TNWP2GAfF5Dnvfsqo665rbefq2-af2hdzpGF8</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase</title><source>ACS Publications</source><creator>DENNY, B. J ; RINGAN, N. S ; SCHWALBE, C. H ; LAMBERT, P. A ; MEEK, M. A ; GRIFFIN, R. J ; STEVENS, M. F. G</creator><creatorcontrib>DENNY, B. J ; RINGAN, N. S ; SCHWALBE, C. H ; LAMBERT, P. A ; MEEK, M. A ; GRIFFIN, R. J ; STEVENS, M. F. G</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>CODEN: JMCMAR</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Analytical, structural and metabolic biochemistry ; Biological and medical sciences ; Enzymes and enzyme inhibitors ; Fundamental and applied biological sciences. Psychology ; Oxidoreductases</subject><ispartof>Journal of medicinal chemistry, 1992, Vol.35 (12), p.2315-2320</ispartof><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=5405219$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>DENNY, B. J</creatorcontrib><creatorcontrib>RINGAN, N. S</creatorcontrib><creatorcontrib>SCHWALBE, C. H</creatorcontrib><creatorcontrib>LAMBERT, P. A</creatorcontrib><creatorcontrib>MEEK, M. A</creatorcontrib><creatorcontrib>GRIFFIN, R. J</creatorcontrib><creatorcontrib>STEVENS, M. F. G</creatorcontrib><title>Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase</title><title>Journal of medicinal chemistry</title><subject>Analytical, structural and metabolic biochemistry</subject><subject>Biological and medical sciences</subject><subject>Enzymes and enzyme inhibitors</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Oxidoreductases</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><recordid>eNqNjrtOxDAQAC0EEsfjH7agJMhxEgS0CERDBcV1p429uSxyvNHaQQp_w58CEgUl1TSj0RyYTd05W7U3tj00G2udq9y1a47NSc5v1tqmds3GfL4UXXxZFCPksgSmDJKgZ6nQF34n8DLNsqSQr2C7vYNnieSXiAqTBIqc9oApgNc1F4xR9orzyP5vbKIyrrGn9CGz8nQJCLMUSgU4jdxzEQUZIPC4BpVBIhYCpfD9hZnOzNGAMdP5L0_NxePD6_1TNWP2GAfF5Dnvfsqo665rbefq2-af2hdzpGF8</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>DENNY, B. J</creator><creator>RINGAN, N. S</creator><creator>SCHWALBE, C. H</creator><creator>LAMBERT, P. A</creator><creator>MEEK, M. A</creator><creator>GRIFFIN, R. J</creator><creator>STEVENS, M. F. G</creator><general>American Chemical Society</general><scope>IQODW</scope></search><sort><creationdate>1992</creationdate><title>Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase</title><author>DENNY, B. J ; RINGAN, N. S ; SCHWALBE, C. H ; LAMBERT, P. A ; MEEK, M. A ; GRIFFIN, R. J ; STEVENS, M. F. G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pascalfrancis_primary_54052193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Analytical, structural and metabolic biochemistry</topic><topic>Biological and medical sciences</topic><topic>Enzymes and enzyme inhibitors</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Oxidoreductases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DENNY, B. J</creatorcontrib><creatorcontrib>RINGAN, N. S</creatorcontrib><creatorcontrib>SCHWALBE, C. H</creatorcontrib><creatorcontrib>LAMBERT, P. A</creatorcontrib><creatorcontrib>MEEK, M. A</creatorcontrib><creatorcontrib>GRIFFIN, R. J</creatorcontrib><creatorcontrib>STEVENS, M. F. G</creatorcontrib><collection>Pascal-Francis</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DENNY, B. J</au><au>RINGAN, N. S</au><au>SCHWALBE, C. H</au><au>LAMBERT, P. A</au><au>MEEK, M. A</au><au>GRIFFIN, R. J</au><au>STEVENS, M. F. G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase</atitle><jtitle>Journal of medicinal chemistry</jtitle><date>1992</date><risdate>1992</risdate><volume>35</volume><issue>12</issue><spage>2315</spage><epage>2320</epage><pages>2315-2320</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><coden>JMCMAR</coden><cop>Washington, DC</cop><pub>American Chemical Society</pub></addata></record>
fulltext fulltext
identifier ISSN: 0022-2623
ispartof Journal of medicinal chemistry, 1992, Vol.35 (12), p.2315-2320
issn 0022-2623
1520-4804
language eng
recordid cdi_pascalfrancis_primary_5405219
source ACS Publications
subjects Analytical, structural and metabolic biochemistry
Biological and medical sciences
Enzymes and enzyme inhibitors
Fundamental and applied biological sciences. Psychology
Oxidoreductases
title Structural studies on bio-active compounds. XX: Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T05%3A20%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pascalfrancis&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Structural%20studies%20on%20bio-active%20compounds.%20XX:%20Molecular%20modeling%20and%20crystallographic%20studies%20on%20methylbenzoprim,%20a%20potent%20inhibitor%20of%20dihydrofolate%20reductase&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=DENNY,%20B.%20J&rft.date=1992&rft.volume=35&rft.issue=12&rft.spage=2315&rft.epage=2320&rft.pages=2315-2320&rft.issn=0022-2623&rft.eissn=1520-4804&rft.coden=JMCMAR&rft_id=info:doi/&rft_dat=%3Cpascalfrancis%3E5405219%3C/pascalfrancis%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true