Synthesis of α1‐microglobulin in cultured rat hepatocytes is stimulated by interleukin‐6, leukemia inhibitory factor, dexamethasone and retinoic acid

The secretion or α1‐microglobulin by primary cultures of rat hepatocytes was found to increase upon the addition of interleukin‐6 or leukemia inhibitory factor, two mediators of acute phase response. This stimulatory effect was further enhanced by dexamethasone. α1‐Microglobulin is synthesized as a...

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Veröffentlicht in:	FEBS letters 1992-02, Vol.298 (2-3), p.165-168
Hauptverfasser:	Pierzchalski, Piotr, Rokita, Hanna, Koj, Aleksander, Fries, Erik, Åkerström, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute phase Bikunin Biological and medical sciences CPI cysteine proteinase inhibitor Fundamental and applied biological sciences. Psychology IL-6 Inflammation Interleukin-6 leukemia inhibitory factor LIF Molecular and cellular biology Rat hepatocyte Retionoic acid SDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresis α1-m α1-Microglobulin
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