A simple approach to homotropanes and homotrop-7-enes

1,4-Functionalisatio of cycloocta-1,3-diene using a nitroso-cycloaddition strategy is followed by intramolecular cyclisation to yield 9-azabicyclo[4.2.1]nonanes (homotropanes) and -non-7-enes (homotrop-7-enes); the approach can be adapted to allow access to 1-methylhomotropanes.

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Bibliographische Detailangaben
Veröffentlicht in:	Tetrahedron letters 1992, Vol.33 (2), p.273-276
Hauptverfasser:	Malpass, John R., Smith, Craig
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry, Organic Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Organic chemistry Physical Sciences Preparations and properties Science & Technology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	1,4-Functionalisatio of cycloocta-1,3-diene using a nitroso-cycloaddition strategy is followed by intramolecular cyclisation to yield 9-azabicyclo[4.2.1]nonanes (homotropanes) and -non-7-enes (homotrop-7-enes); the approach can be adapted to allow access to 1-methylhomotropanes.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/0040-4039(92)88069-H