Neuroblastoma: Effect of genetic factors on prognosis and treatment

Background and Methods. Genetic analysis of tumor tissue has provided considerable insight into mechanisms of malignant transformation and progression. Neuroblastomas have been studied by cytogenetics, flow cytometry, and molecular genetic techniques, and these studies have identified several specif...

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Veröffentlicht in:	Cancer 1992-09, Vol.70 (S4), p.1685-1694
Hauptverfasser:	Brodeur, Garrett M., Azar, Christopher, Brother, Michele, Hiemstra, Jill, Kaufman, Bruce, Marshall, Helen, Moley, Jeffrey, Nakagawara, Akira, Saylors, Robert, Scavarda, Nancy, Schneider, Sandra, Wasson, Jonathon, White, Peter, Seeger, Robert, Look, Thomas, Castleberry, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line Chromosome Aberrations - genetics Chromosome Deletion Chromosome Disorders deletion of chromosome Ip Gene Amplification Genes, myc Genetic Techniques Humans Infant Life Sciences & Biomedicine loss of heterozygosity (LOH) Medical sciences molecular genetics neuroblastoma Neuroblastoma - classification Neuroblastoma - genetics Neuroblastoma - therapy Neurology NGF receptor (NGFR) N‐myc amplification oncogenes Oncology Ploidies Prognosis prognostic factors Receptors, Cell Surface - genetics Receptors, Nerve Growth Factor Science & Technology suppressor genes tumor cell DNA content Tumors of the nervous system. Phacomatoses
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