Ion-Pairing of Dyclonine with Dyes

Abstract This potential for ion-pairing between dyclonine, a local anesthetic, and pharmaceutical dyes commonly used in liquid pharmaceutical formulations was examined. Occurrence of ion-pairing at a pH of 3 was confirmed by shift of the absorption maximum of all five sulfonate-containing dyes, and...

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Veröffentlicht in:	Drug development and industrial pharmacy 1993, Vol.19 (11), p.1265-1282
Hauptverfasser:	Chen, Chun-Ren, Zatz, Joel L., Reilly, Eugene
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General pharmacology Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments
Online-Zugang:	Volltext
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