Functional imaging of human motor cortex at high magnetic field
S. G. Kim, J. Ashe, A. P. Georgopoulos, H. Merkle, J. M. Ellermann, R. S. Menon, S. Ogawa and K. Ugurbil Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455. 1. We used conventional gradient echo magnetic resonance imaging (MRI) at high field strength (4...
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| Veröffentlicht in: | Journal of neurophysiology 1993-01, Vol.69 (1), p.297-302 |
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| container_title | Journal of neurophysiology |
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| creator | Kim, S. G Ashe, J Georgopoulos, A. P Merkle, H Ellermann, J. M Menon, R. S Ogawa, S Ugurbil, K |
| description | S. G. Kim, J. Ashe, A. P. Georgopoulos, H. Merkle, J. M. Ellermann, R. S. Menon, S. Ogawa and K. Ugurbil
Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455.
1. We used conventional gradient echo magnetic resonance imaging (MRI) at
high field strength (4 Tesla) to functionally image the right motor cortex
in six normal human subjects during the performance of a sequence of
self-paced thumb to digit oppositions with the left hand (contralateral
task), the right hand (ipsilateral task), and both hands (bilateral task).
2. A localized increase in activity in the lateral motor cortex was
observed in all subjects during the task. The area of activation was
similar in the contralateral and bilateral tasks but 20 times smaller in
the ipsilateral task. The intensity of activation was 2.3 times greater in
the contralateral than the ipsilateral task. |
| doi_str_mv | 10.1152/jn.1993.69.1.297 |
| format | Article |
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Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455.
1. We used conventional gradient echo magnetic resonance imaging (MRI) at
high field strength (4 Tesla) to functionally image the right motor cortex
in six normal human subjects during the performance of a sequence of
self-paced thumb to digit oppositions with the left hand (contralateral
task), the right hand (ipsilateral task), and both hands (bilateral task).
2. A localized increase in activity in the lateral motor cortex was
observed in all subjects during the task. The area of activation was
similar in the contralateral and bilateral tasks but 20 times smaller in
the ipsilateral task. The intensity of activation was 2.3 times greater in
the contralateral than the ipsilateral task.</description><identifier>ISSN: 0022-3077</identifier><identifier>EISSN: 1522-1598</identifier><identifier>DOI: 10.1152/jn.1993.69.1.297</identifier><identifier>PMID: 8433133</identifier><identifier>CODEN: JONEA4</identifier><language>eng</language><publisher>Bethesda, MD: Am Phys Soc</publisher><subject>Adult ; Arousal - physiology ; Biological and medical sciences ; Brain Mapping ; Evoked Potentials - physiology ; Functional Laterality - physiology ; Fundamental and applied biological sciences. Psychology ; Humans ; Magnetic Resonance Imaging ; Motor Activity - physiology ; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration ; Motor Cortex - physiology ; Muscle Contraction - physiology ; Vertebrates: nervous system and sense organs</subject><ispartof>Journal of neurophysiology, 1993-01, Vol.69 (1), p.297-302</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-ce9adc217a1a5b16084b72fb5c0c8a23127451b4b5137320ddd2f9bbe8e143f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,4010,27904,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4517450$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8433133$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, S. G</creatorcontrib><creatorcontrib>Ashe, J</creatorcontrib><creatorcontrib>Georgopoulos, A. P</creatorcontrib><creatorcontrib>Merkle, H</creatorcontrib><creatorcontrib>Ellermann, J. M</creatorcontrib><creatorcontrib>Menon, R. S</creatorcontrib><creatorcontrib>Ogawa, S</creatorcontrib><creatorcontrib>Ugurbil, K</creatorcontrib><title>Functional imaging of human motor cortex at high magnetic field</title><title>Journal of neurophysiology</title><addtitle>J Neurophysiol</addtitle><description>S. G. Kim, J. Ashe, A. P. Georgopoulos, H. Merkle, J. M. Ellermann, R. S. Menon, S. Ogawa and K. Ugurbil
Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455.
1. We used conventional gradient echo magnetic resonance imaging (MRI) at
high field strength (4 Tesla) to functionally image the right motor cortex
in six normal human subjects during the performance of a sequence of
self-paced thumb to digit oppositions with the left hand (contralateral
task), the right hand (ipsilateral task), and both hands (bilateral task).
2. A localized increase in activity in the lateral motor cortex was
observed in all subjects during the task. The area of activation was
similar in the contralateral and bilateral tasks but 20 times smaller in
the ipsilateral task. The intensity of activation was 2.3 times greater in
the contralateral than the ipsilateral task.</description><subject>Adult</subject><subject>Arousal - physiology</subject><subject>Biological and medical sciences</subject><subject>Brain Mapping</subject><subject>Evoked Potentials - physiology</subject><subject>Functional Laterality - physiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Motor Activity - physiology</subject><subject>Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration</subject><subject>Motor Cortex - physiology</subject><subject>Muscle Contraction - physiology</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0022-3077</issn><issn>1522-1598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPxCAQgInR6Pq4ezHhYLxtZaCUcjLG-EpMvHgnlNJdNi2s0Eb338vGzXr0xIT55vUhdAmkAOD0duULkJIVlSygoFIcoFn-pnPgsj5EM0JyzIgQJ-g0pRUhRHBCj9FxXTIGjM3Q3dPkzeiC1z12g144v8Chw8tp0B4PYQwRmxBH-431iJduscQZ8nZ0BnfO9u05Oup0n-zF7j1DH0-PHw8v87f359eH-7e5KTmMc2Olbg0FoUHzBipSl42gXcMNMbWmDKjIXFM2HJhglLRtSzvZNLa2ULKOnaGb37brGD4nm0Y1uGRs32tvw5SU4LySVIh_Qag4Y4LQDJJf0MSQUrSdWscsIG4UELV1q1Zebd2qSipQ2W0uudr1nprBtvuCncycv97ldTK676L2xqU9lg_MR5K_Fbc6v1y0ar3cJBf6sNhsh-7n_QDG5I5d</recordid><startdate>19930101</startdate><enddate>19930101</enddate><creator>Kim, S. G</creator><creator>Ashe, J</creator><creator>Georgopoulos, A. P</creator><creator>Merkle, H</creator><creator>Ellermann, J. M</creator><creator>Menon, R. S</creator><creator>Ogawa, S</creator><creator>Ugurbil, K</creator><general>Am Phys Soc</general><general>American Physiological Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19930101</creationdate><title>Functional imaging of human motor cortex at high magnetic field</title><author>Kim, S. G ; Ashe, J ; Georgopoulos, A. P ; Merkle, H ; Ellermann, J. M ; Menon, R. S ; Ogawa, S ; Ugurbil, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-ce9adc217a1a5b16084b72fb5c0c8a23127451b4b5137320ddd2f9bbe8e143f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adult</topic><topic>Arousal - physiology</topic><topic>Biological and medical sciences</topic><topic>Brain Mapping</topic><topic>Evoked Potentials - physiology</topic><topic>Functional Laterality - physiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Motor Activity - physiology</topic><topic>Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration</topic><topic>Motor Cortex - physiology</topic><topic>Muscle Contraction - physiology</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, S. G</creatorcontrib><creatorcontrib>Ashe, J</creatorcontrib><creatorcontrib>Georgopoulos, A. P</creatorcontrib><creatorcontrib>Merkle, H</creatorcontrib><creatorcontrib>Ellermann, J. M</creatorcontrib><creatorcontrib>Menon, R. S</creatorcontrib><creatorcontrib>Ogawa, S</creatorcontrib><creatorcontrib>Ugurbil, K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of neurophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, S. G</au><au>Ashe, J</au><au>Georgopoulos, A. P</au><au>Merkle, H</au><au>Ellermann, J. M</au><au>Menon, R. S</au><au>Ogawa, S</au><au>Ugurbil, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional imaging of human motor cortex at high magnetic field</atitle><jtitle>Journal of neurophysiology</jtitle><addtitle>J Neurophysiol</addtitle><date>1993-01-01</date><risdate>1993</risdate><volume>69</volume><issue>1</issue><spage>297</spage><epage>302</epage><pages>297-302</pages><issn>0022-3077</issn><eissn>1522-1598</eissn><coden>JONEA4</coden><abstract>S. G. Kim, J. Ashe, A. P. Georgopoulos, H. Merkle, J. M. Ellermann, R. S. Menon, S. Ogawa and K. Ugurbil
Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455.
1. We used conventional gradient echo magnetic resonance imaging (MRI) at
high field strength (4 Tesla) to functionally image the right motor cortex
in six normal human subjects during the performance of a sequence of
self-paced thumb to digit oppositions with the left hand (contralateral
task), the right hand (ipsilateral task), and both hands (bilateral task).
2. A localized increase in activity in the lateral motor cortex was
observed in all subjects during the task. The area of activation was
similar in the contralateral and bilateral tasks but 20 times smaller in
the ipsilateral task. The intensity of activation was 2.3 times greater in
the contralateral than the ipsilateral task.</abstract><cop>Bethesda, MD</cop><pub>Am Phys Soc</pub><pmid>8433133</pmid><doi>10.1152/jn.1993.69.1.297</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Arousal - physiology Biological and medical sciences Brain Mapping Evoked Potentials - physiology Functional Laterality - physiology Fundamental and applied biological sciences. Psychology Humans Magnetic Resonance Imaging Motor Activity - physiology Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Motor Cortex - physiology Muscle Contraction - physiology Vertebrates: nervous system and sense organs |
| title | Functional imaging of human motor cortex at high magnetic field |
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