On-line coupled reversed-phase high-performance liquid chromatography—gas chromatography—mass spectrometry: A powerful tool for the identification of unknown impurities in pharmaceutical products

An alternative approach to HPLC—MS involving direct coupling of reversed-phase HPLC to GC—MS is described for the identification of unknown impurities in pharmaceutical products. Conventional-sized reversed-phase HPLC (column of 4.6 mm I.D., flow-rate 2 ml/min) was coupled to GCMS. Liquid sample vo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of Chromatography A 1992-01, Vol.626 (1), p.87-96
Hauptverfasser:	Ogorka, Jörg, Schwinger, Gerhard, Bruat, Guy, Seidel, Volker
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Exact sciences and technology Miscellaneous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!