Distribution of β-thalassemia mutations in three asian indian populations with distant geographical locations

We have identified the β-thalassemia alleles in 47 pediatric patients with transfusion-dependent thalassemia major from a clinic in New Delhi and in 105 heterozygous relatives. Surprisingly, only five mutations were present in 94 β-thalassemia chromosomes with frequencies from 10 to 32%. This observ...

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