Hepatoma cells adapted to proliferate under normally lethal hyperthermic stress conditions show rapid decay of thermoresistance and heat shock protein synthesis when returned to 37°C

H35 hepatoma cultures were adapted to sustained growth at 41·3°C. In these variant cells the 'basic' levels of various heat shock proteins (hsps), especially those of hsp60, 70 and 100, are significantly raised. These cells exhibit a thermoresistance comparable with the induced thermotoler...

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Veröffentlicht in:International journal of hyperthermia 1995, Vol.11 (5), p.697-708
Hauptverfasser: van Rijn, J., van den Berg, J., Souren, J. E. M., van Wijk, R., Joenje, H.
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Sprache:eng
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