Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes
Abstract To control benzodiazepine abuse in Hong Kong, the Government's Pharmacy and Poisons Board reclassified benzodiazepines as Dangerous Drugs in October 1990. Apart from formal prescriptions, detailed records were then required for the supply and dispensing of these drugs. These regulation...
Gespeichert in:
| Veröffentlicht in: | Clinical toxicology (Philadelphia, Pa.) Pa.), 1995, Vol.33 (6), p.597-602 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 602 |
|---|---|
| container_issue | 6 |
| container_start_page | 597 |
| container_title | Clinical toxicology (Philadelphia, Pa.) |
| container_volume | 33 |
| creator | Lee, Kenneth K.C. Chan, Thomas Y.K. Chan, Anthony W.K. Lau, Grace S.N. Critchley, Julian A.J.H. |
| description | Abstract
To control benzodiazepine abuse in Hong Kong, the Government's Pharmacy and Poisons Board reclassified benzodiazepines as Dangerous Drugs in October 1990. Apart from formal prescriptions, detailed records were then required for the supply and dispensing of these drugs. These regulations were applied initially only to brotizolam, triazolam and flunitrazepam, and were extended in January 1992 to include all benzodiazepines. The impact of these regulatory changes on benzodiazepine use has been studied by analyzing the sales patterns of seven benzodiazepines between 1990-1993. In 1991, the sales of flunitrazepam and triazolam fell, but the sales of five unrestricted benzodiazepines increased. In 1992-1993, the sales of all but one of the benzodiazepines fell. Comparing 1993 to 1990, the fall in sales was particularly marked for triazolam, chlordiazepoxide and flunitrazepam. A regulation requiring the use of proper prescriptions and detailed records for the supply and dispensing of benzodiazepines, appears to have curbed, at least partially, their abuse in Hong Kong. |
| doi_str_mv | 10.3109/15563659509010615 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_pasca</sourceid><recordid>TN_cdi_pascalfrancis_primary_2937149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>8523479</sourcerecordid><originalsourceid>FETCH-LOGICAL-c430t-8eabe8333d8ebdb8fb46d90fcc6ba2dfd6c6232f42ab85b2cefd52dfacb509f3</originalsourceid><addsrcrecordid>eNp9kE1LxDAQhoMoun78AA9CDl6rSdPUBr2si18oCLJevJTJ17bSJkvSRXZ_vS27CiLsZWaYeZ9h5kXolJILRom4pJznLOeCE0EoySnfQaOhlwhOxe6m7gXkAB3G-EkIKzJB99F-wVOWXYkR-niPBoPTeCwXfeUtvjVu5XUNKzOvnYm4dvjRuxl-HgIVgiR9YDjB08rgp3YOqhuwNzNbNND5sMSTCtzMxGO0Z6GJ5mSTj9D0_m46eUxeXh-eJuOXRGWMdElhQJqCMaYLI7UsrMxyLYhVKpeQaqtzlacstVkKsuAyVcZq3vdByf5ty44QXa9VwccYjC3noW4hLEtKysGl8p9LPXO2ZuYL2Rr9S2xs6efnmzlEBY0N4FQdf2WpYFc0G2Q3a1ntrA8tfPnQ6LKDZePDD8O2XXH9B68MNF2lIJjy0y-C603b8sM3x3qTkQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes</title><source>MEDLINE</source><source>Taylor & Francis:Master (3349 titles)</source><source>Taylor & Francis Medical Library - CRKN</source><creator>Lee, Kenneth K.C. ; Chan, Thomas Y.K. ; Chan, Anthony W.K. ; Lau, Grace S.N. ; Critchley, Julian A.J.H.</creator><creatorcontrib>Lee, Kenneth K.C. ; Chan, Thomas Y.K. ; Chan, Anthony W.K. ; Lau, Grace S.N. ; Critchley, Julian A.J.H.</creatorcontrib><description>Abstract
To control benzodiazepine abuse in Hong Kong, the Government's Pharmacy and Poisons Board reclassified benzodiazepines as Dangerous Drugs in October 1990. Apart from formal prescriptions, detailed records were then required for the supply and dispensing of these drugs. These regulations were applied initially only to brotizolam, triazolam and flunitrazepam, and were extended in January 1992 to include all benzodiazepines. The impact of these regulatory changes on benzodiazepine use has been studied by analyzing the sales patterns of seven benzodiazepines between 1990-1993. In 1991, the sales of flunitrazepam and triazolam fell, but the sales of five unrestricted benzodiazepines increased. In 1992-1993, the sales of all but one of the benzodiazepines fell. Comparing 1993 to 1990, the fall in sales was particularly marked for triazolam, chlordiazepoxide and flunitrazepam. A regulation requiring the use of proper prescriptions and detailed records for the supply and dispensing of benzodiazepines, appears to have curbed, at least partially, their abuse in Hong Kong.</description><identifier>ISSN: 1556-3650</identifier><identifier>ISSN: 0731-3810</identifier><identifier>EISSN: 1556-9519</identifier><identifier>EISSN: 1097-9875</identifier><identifier>DOI: 10.3109/15563659509010615</identifier><identifier>PMID: 8523479</identifier><language>eng</language><publisher>Monticello, NY: Informa UK Ltd</publisher><subject>benzodiazepines ; Benzodiazepines - economics ; Benzodiazepines - pharmacology ; Benzodiazepines - poisoning ; Biological and medical sciences ; drue abuse ; Drug and Narcotic Control - statistics & numerical data ; Drug intoxications. Doping ; Drug Prescriptions - economics ; Drug Prescriptions - statistics & numerical data ; Drug Utilization Review - statistics & numerical data ; Hong Kong ; Horn Kong ; Humans ; Medical sciences ; Pharmacology. Drug treatments ; reeulation ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - prevention & control</subject><ispartof>Clinical toxicology (Philadelphia, Pa.), 1995, Vol.33 (6), p.597-602</ispartof><rights>1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1995</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-8eabe8333d8ebdb8fb46d90fcc6ba2dfd6c6232f42ab85b2cefd52dfacb509f3</citedby><cites>FETCH-LOGICAL-c430t-8eabe8333d8ebdb8fb46d90fcc6ba2dfd6c6232f42ab85b2cefd52dfacb509f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/15563659509010615$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/15563659509010615$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,4023,4049,4050,23929,23930,25139,27922,27923,27924,59646,59752,60435,60541,61220,61255,61401,61436</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2937149$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8523479$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Kenneth K.C.</creatorcontrib><creatorcontrib>Chan, Thomas Y.K.</creatorcontrib><creatorcontrib>Chan, Anthony W.K.</creatorcontrib><creatorcontrib>Lau, Grace S.N.</creatorcontrib><creatorcontrib>Critchley, Julian A.J.H.</creatorcontrib><title>Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes</title><title>Clinical toxicology (Philadelphia, Pa.)</title><addtitle>J Toxicol Clin Toxicol</addtitle><description>Abstract
To control benzodiazepine abuse in Hong Kong, the Government's Pharmacy and Poisons Board reclassified benzodiazepines as Dangerous Drugs in October 1990. Apart from formal prescriptions, detailed records were then required for the supply and dispensing of these drugs. These regulations were applied initially only to brotizolam, triazolam and flunitrazepam, and were extended in January 1992 to include all benzodiazepines. The impact of these regulatory changes on benzodiazepine use has been studied by analyzing the sales patterns of seven benzodiazepines between 1990-1993. In 1991, the sales of flunitrazepam and triazolam fell, but the sales of five unrestricted benzodiazepines increased. In 1992-1993, the sales of all but one of the benzodiazepines fell. Comparing 1993 to 1990, the fall in sales was particularly marked for triazolam, chlordiazepoxide and flunitrazepam. A regulation requiring the use of proper prescriptions and detailed records for the supply and dispensing of benzodiazepines, appears to have curbed, at least partially, their abuse in Hong Kong.</description><subject>benzodiazepines</subject><subject>Benzodiazepines - economics</subject><subject>Benzodiazepines - pharmacology</subject><subject>Benzodiazepines - poisoning</subject><subject>Biological and medical sciences</subject><subject>drue abuse</subject><subject>Drug and Narcotic Control - statistics & numerical data</subject><subject>Drug intoxications. Doping</subject><subject>Drug Prescriptions - economics</subject><subject>Drug Prescriptions - statistics & numerical data</subject><subject>Drug Utilization Review - statistics & numerical data</subject><subject>Hong Kong</subject><subject>Horn Kong</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>reeulation</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Substance-Related Disorders - prevention & control</subject><issn>1556-3650</issn><issn>0731-3810</issn><issn>1556-9519</issn><issn>1097-9875</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMoun78AA9CDl6rSdPUBr2si18oCLJevJTJ17bSJkvSRXZ_vS27CiLsZWaYeZ9h5kXolJILRom4pJznLOeCE0EoySnfQaOhlwhOxe6m7gXkAB3G-EkIKzJB99F-wVOWXYkR-niPBoPTeCwXfeUtvjVu5XUNKzOvnYm4dvjRuxl-HgIVgiR9YDjB08rgp3YOqhuwNzNbNND5sMSTCtzMxGO0Z6GJ5mSTj9D0_m46eUxeXh-eJuOXRGWMdElhQJqCMaYLI7UsrMxyLYhVKpeQaqtzlacstVkKsuAyVcZq3vdByf5ty44QXa9VwccYjC3noW4hLEtKysGl8p9LPXO2ZuYL2Rr9S2xs6efnmzlEBY0N4FQdf2WpYFc0G2Q3a1ntrA8tfPnQ6LKDZePDD8O2XXH9B68MNF2lIJjy0y-C603b8sM3x3qTkQ</recordid><startdate>1995</startdate><enddate>1995</enddate><creator>Lee, Kenneth K.C.</creator><creator>Chan, Thomas Y.K.</creator><creator>Chan, Anthony W.K.</creator><creator>Lau, Grace S.N.</creator><creator>Critchley, Julian A.J.H.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Dekker</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1995</creationdate><title>Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes</title><author>Lee, Kenneth K.C. ; Chan, Thomas Y.K. ; Chan, Anthony W.K. ; Lau, Grace S.N. ; Critchley, Julian A.J.H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-8eabe8333d8ebdb8fb46d90fcc6ba2dfd6c6232f42ab85b2cefd52dfacb509f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>benzodiazepines</topic><topic>Benzodiazepines - economics</topic><topic>Benzodiazepines - pharmacology</topic><topic>Benzodiazepines - poisoning</topic><topic>Biological and medical sciences</topic><topic>drue abuse</topic><topic>Drug and Narcotic Control - statistics & numerical data</topic><topic>Drug intoxications. Doping</topic><topic>Drug Prescriptions - economics</topic><topic>Drug Prescriptions - statistics & numerical data</topic><topic>Drug Utilization Review - statistics & numerical data</topic><topic>Hong Kong</topic><topic>Horn Kong</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>reeulation</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Kenneth K.C.</creatorcontrib><creatorcontrib>Chan, Thomas Y.K.</creatorcontrib><creatorcontrib>Chan, Anthony W.K.</creatorcontrib><creatorcontrib>Lau, Grace S.N.</creatorcontrib><creatorcontrib>Critchley, Julian A.J.H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Clinical toxicology (Philadelphia, Pa.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Kenneth K.C.</au><au>Chan, Thomas Y.K.</au><au>Chan, Anthony W.K.</au><au>Lau, Grace S.N.</au><au>Critchley, Julian A.J.H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes</atitle><jtitle>Clinical toxicology (Philadelphia, Pa.)</jtitle><addtitle>J Toxicol Clin Toxicol</addtitle><date>1995</date><risdate>1995</risdate><volume>33</volume><issue>6</issue><spage>597</spage><epage>602</epage><pages>597-602</pages><issn>1556-3650</issn><issn>0731-3810</issn><eissn>1556-9519</eissn><eissn>1097-9875</eissn><abstract>Abstract
To control benzodiazepine abuse in Hong Kong, the Government's Pharmacy and Poisons Board reclassified benzodiazepines as Dangerous Drugs in October 1990. Apart from formal prescriptions, detailed records were then required for the supply and dispensing of these drugs. These regulations were applied initially only to brotizolam, triazolam and flunitrazepam, and were extended in January 1992 to include all benzodiazepines. The impact of these regulatory changes on benzodiazepine use has been studied by analyzing the sales patterns of seven benzodiazepines between 1990-1993. In 1991, the sales of flunitrazepam and triazolam fell, but the sales of five unrestricted benzodiazepines increased. In 1992-1993, the sales of all but one of the benzodiazepines fell. Comparing 1993 to 1990, the fall in sales was particularly marked for triazolam, chlordiazepoxide and flunitrazepam. A regulation requiring the use of proper prescriptions and detailed records for the supply and dispensing of benzodiazepines, appears to have curbed, at least partially, their abuse in Hong Kong.</abstract><cop>Monticello, NY</cop><pub>Informa UK Ltd</pub><pmid>8523479</pmid><doi>10.3109/15563659509010615</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1556-3650 |
| ispartof | Clinical toxicology (Philadelphia, Pa.), 1995, Vol.33 (6), p.597-602 |
| issn | 1556-3650 0731-3810 1556-9519 1097-9875 |
| language | eng |
| recordid | cdi_pascalfrancis_primary_2937149 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | benzodiazepines Benzodiazepines - economics Benzodiazepines - pharmacology Benzodiazepines - poisoning Biological and medical sciences drue abuse Drug and Narcotic Control - statistics & numerical data Drug intoxications. Doping Drug Prescriptions - economics Drug Prescriptions - statistics & numerical data Drug Utilization Review - statistics & numerical data Hong Kong Horn Kong Humans Medical sciences Pharmacology. Drug treatments reeulation Substance-Related Disorders - epidemiology Substance-Related Disorders - prevention & control |
| title | Use and Abuse of Benzodiazepines in Hong Kong 1990-1993 - The Impact of Regulatory Changes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T18%3A07%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Use%20and%20Abuse%20of%20Benzodiazepines%20in%20Hong%20Kong%201990-1993%20-%20The%20Impact%20of%20Regulatory%20Changes&rft.jtitle=Clinical%20toxicology%20(Philadelphia,%20Pa.)&rft.au=Lee,%20Kenneth%20K.C.&rft.date=1995&rft.volume=33&rft.issue=6&rft.spage=597&rft.epage=602&rft.pages=597-602&rft.issn=1556-3650&rft.eissn=1556-9519&rft_id=info:doi/10.3109/15563659509010615&rft_dat=%3Cpubmed_pasca%3E8523479%3C/pubmed_pasca%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/8523479&rfr_iscdi=true |