Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2013-11, Vol.57 (11), p.5344-5354 |
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| creator | Wu, Guoyi Liu, Bo Zhang, Yingjun Li, Jing Arzumanyan, Alla Clayton, Marcia M Schinazi, Raymond F Wang, Zhaohe Goldmann, Siegfried Ren, Qingyun Zhang, Faxhou Feitelson, Mark A |
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| doi_str_mv | 10.1128/aac.01091-13 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.01091-13</identifier><identifier>PMID: 23959305</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Alanine transaminase ; Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - chemical synthesis ; Antiviral Agents - pharmacology ; Biological and medical sciences ; Cell Line ; DNA, Viral ; DNA, Viral - antagonists & inhibitors ; DNA, Viral - biosynthesis ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Hepatitis B virus ; Hepatitis B virus - drug effects ; Hepatitis B virus - growth & development ; Hepatitis B virus - ultrastructure ; Hepatitis B, Chronic ; Hepatitis B, Chronic - drug therapy ; Hepatitis B, Chronic - virology ; Hepatocytes - drug effects ; Hepatocytes - pathology ; Hepatocytes - virology ; Human viral diseases ; Humans ; Infectious diseases ; Lamivudine - pharmacology ; Male ; Medical sciences ; Mice ; Mice, Nude ; Microbial Sensitivity Tests ; Pharmacology. Drug treatments ; Primary Cell Culture ; Pyridines - pharmacology ; Pyrimidines ; Pyrimidines - chemical synthesis ; Pyrimidines - pharmacology ; Thiazoles ; Thiazoles - chemical synthesis ; Thiazoles - pharmacology ; Viral Core Proteins - antagonists & inhibitors ; Viral Core Proteins - metabolism ; Viral diseases ; Viral hepatitis ; Viremia ; Viremia - drug therapy ; Viremia - virology ; Virion ; Virion - drug effects ; Virion - ultrastructure ; Virus Replication - drug effects</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2013-11, Vol.57 (11), p.5344-5354</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a574t-89d7860841f6370d071d78733485b9d1cb086e3ab859577a904cba87940ad6ee3</citedby><cites>FETCH-LOGICAL-a574t-89d7860841f6370d071d78733485b9d1cb086e3ab859577a904cba87940ad6ee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811253/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811253/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27921454$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23959305$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wu, Guoyi</creatorcontrib><creatorcontrib>Liu, Bo</creatorcontrib><creatorcontrib>Zhang, Yingjun</creatorcontrib><creatorcontrib>Li, Jing</creatorcontrib><creatorcontrib>Arzumanyan, Alla</creatorcontrib><creatorcontrib>Clayton, Marcia M</creatorcontrib><creatorcontrib>Schinazi, Raymond F</creatorcontrib><creatorcontrib>Wang, Zhaohe</creatorcontrib><creatorcontrib>Goldmann, Siegfried</creatorcontrib><creatorcontrib>Ren, Qingyun</creatorcontrib><creatorcontrib>Zhang, Faxhou</creatorcontrib><creatorcontrib>Feitelson, Mark A</creatorcontrib><title>Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Alanine transaminase</subject><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Antiviral Agents - chemical synthesis</subject><subject>Antiviral Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Cell Line</subject><subject>DNA, Viral</subject><subject>DNA, Viral - antagonists & inhibitors</subject><subject>DNA, Viral - biosynthesis</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Evaluation, Preclinical</subject><subject>Hepatitis B virus</subject><subject>Hepatitis B virus - drug effects</subject><subject>Hepatitis B virus - growth & development</subject><subject>Hepatitis B virus - ultrastructure</subject><subject>Hepatitis B, Chronic</subject><subject>Hepatitis B, Chronic - drug therapy</subject><subject>Hepatitis B, Chronic - virology</subject><subject>Hepatocytes - drug effects</subject><subject>Hepatocytes - pathology</subject><subject>Hepatocytes - virology</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Lamivudine - pharmacology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Nude</subject><subject>Microbial Sensitivity Tests</subject><subject>Pharmacology. Drug treatments</subject><subject>Primary Cell Culture</subject><subject>Pyridines - pharmacology</subject><subject>Pyrimidines</subject><subject>Pyrimidines - chemical synthesis</subject><subject>Pyrimidines - pharmacology</subject><subject>Thiazoles</subject><subject>Thiazoles - chemical synthesis</subject><subject>Thiazoles - pharmacology</subject><subject>Viral Core Proteins - antagonists & inhibitors</subject><subject>Viral Core Proteins - metabolism</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><subject>Viremia</subject><subject>Viremia - drug therapy</subject><subject>Viremia - virology</subject><subject>Virion</subject><subject>Virion - drug effects</subject><subject>Virion - ultrastructure</subject><subject>Virus Replication - drug effects</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kt1rFDEUxYModq2--SxBECx0arJJJsmLsB3sByxY8OPRcCeT6aTMTLbJTKX-9WbdteqDT0lufpxzc08QeknJCaVL9Q7AnhBKNC0oe4QWeaeKUujyMVoQUpYFV4QfoGcp3ZB8Fpo8RQdLpoVmRCzQt6vobO9Hb6HHVQcR7OSi_wGTDyMOLT5ff-LHGEZ8OXa-9lOI2-qF22Ri8gmf4q8-zglXITp8BXHytnd4lZIb6v7-OXrSQp_ci_16iL6cffhcXRTrj-eX1WpdgJB8KpRupCqJ4rQtmSQNkTQXJGNciVo31NZElY5BrYQWUoIm3NagpOYEmtI5doje73Q3cz24xrpxitCbTfQDxHsTwJt_b0bfmetwZ5jKQxQsC7zdC8RwO7s0mcEn6_oeRhfmZCgXSjClS57R4x1qY0gpuvbBhhKzjcSsVpX5FYmhW-WjHQ5pWJqbMMcxT-J_7Ku_n_Eg_DuvDLzZA5ByYm2E0fr0h5N6mTvd9vh6x3X-uvvuozPZ3eSvYoTMvkYwztlPTQarAQ</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>Wu, Guoyi</creator><creator>Liu, Bo</creator><creator>Zhang, Yingjun</creator><creator>Li, Jing</creator><creator>Arzumanyan, Alla</creator><creator>Clayton, Marcia M</creator><creator>Schinazi, Raymond F</creator><creator>Wang, Zhaohe</creator><creator>Goldmann, Siegfried</creator><creator>Ren, Qingyun</creator><creator>Zhang, Faxhou</creator><creator>Feitelson, Mark A</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>20131101</creationdate><title>Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly</title><author>Wu, Guoyi ; Liu, Bo ; Zhang, Yingjun ; Li, Jing ; Arzumanyan, Alla ; Clayton, Marcia M ; Schinazi, Raymond F ; Wang, Zhaohe ; Goldmann, Siegfried ; Ren, Qingyun ; Zhang, Faxhou ; Feitelson, Mark A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a574t-89d7860841f6370d071d78733485b9d1cb086e3ab859577a904cba87940ad6ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Alanine transaminase</topic><topic>Animals</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Antiviral Agents - chemical synthesis</topic><topic>Antiviral Agents - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Cell Line</topic><topic>DNA, Viral</topic><topic>DNA, Viral - antagonists & inhibitors</topic><topic>DNA, Viral - biosynthesis</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Evaluation, Preclinical</topic><topic>Hepatitis B virus</topic><topic>Hepatitis B virus - drug effects</topic><topic>Hepatitis B virus - growth & development</topic><topic>Hepatitis B virus - ultrastructure</topic><topic>Hepatitis B, Chronic</topic><topic>Hepatitis B, Chronic - drug therapy</topic><topic>Hepatitis B, Chronic - virology</topic><topic>Hepatocytes - drug effects</topic><topic>Hepatocytes - pathology</topic><topic>Hepatocytes - virology</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Lamivudine - pharmacology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Nude</topic><topic>Microbial Sensitivity Tests</topic><topic>Pharmacology. Drug treatments</topic><topic>Primary Cell Culture</topic><topic>Pyridines - pharmacology</topic><topic>Pyrimidines</topic><topic>Pyrimidines - chemical synthesis</topic><topic>Pyrimidines - pharmacology</topic><topic>Thiazoles</topic><topic>Thiazoles - chemical synthesis</topic><topic>Thiazoles - pharmacology</topic><topic>Viral Core Proteins - antagonists & inhibitors</topic><topic>Viral Core Proteins - metabolism</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><topic>Viremia</topic><topic>Viremia - drug therapy</topic><topic>Viremia - virology</topic><topic>Virion</topic><topic>Virion - drug effects</topic><topic>Virion - ultrastructure</topic><topic>Virus Replication - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Guoyi</creatorcontrib><creatorcontrib>Liu, Bo</creatorcontrib><creatorcontrib>Zhang, Yingjun</creatorcontrib><creatorcontrib>Li, Jing</creatorcontrib><creatorcontrib>Arzumanyan, Alla</creatorcontrib><creatorcontrib>Clayton, Marcia M</creatorcontrib><creatorcontrib>Schinazi, Raymond F</creatorcontrib><creatorcontrib>Wang, Zhaohe</creatorcontrib><creatorcontrib>Goldmann, Siegfried</creatorcontrib><creatorcontrib>Ren, Qingyun</creatorcontrib><creatorcontrib>Zhang, Faxhou</creatorcontrib><creatorcontrib>Feitelson, Mark A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Guoyi</au><au>Liu, Bo</au><au>Zhang, Yingjun</au><au>Li, Jing</au><au>Arzumanyan, Alla</au><au>Clayton, Marcia M</au><au>Schinazi, Raymond F</au><au>Wang, Zhaohe</au><au>Goldmann, Siegfried</au><au>Ren, Qingyun</au><au>Zhang, Faxhou</au><au>Feitelson, Mark A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2013-11-01</date><risdate>2013</risdate><volume>57</volume><issue>11</issue><spage>5344</spage><epage>5354</epage><pages>5344-5354</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>23959305</pmid><doi>10.1128/aac.01091-13</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2013-11, Vol.57 (11), p.5344-5354 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pascalfrancis_primary_27921454 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Alanine transaminase Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - chemical synthesis Antiviral Agents - pharmacology Biological and medical sciences Cell Line DNA, Viral DNA, Viral - antagonists & inhibitors DNA, Viral - biosynthesis Dose-Response Relationship, Drug Drug Evaluation, Preclinical Hepatitis B virus Hepatitis B virus - drug effects Hepatitis B virus - growth & development Hepatitis B virus - ultrastructure Hepatitis B, Chronic Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Hepatocytes - drug effects Hepatocytes - pathology Hepatocytes - virology Human viral diseases Humans Infectious diseases Lamivudine - pharmacology Male Medical sciences Mice Mice, Nude Microbial Sensitivity Tests Pharmacology. Drug treatments Primary Cell Culture Pyridines - pharmacology Pyrimidines Pyrimidines - chemical synthesis Pyrimidines - pharmacology Thiazoles Thiazoles - chemical synthesis Thiazoles - pharmacology Viral Core Proteins - antagonists & inhibitors Viral Core Proteins - metabolism Viral diseases Viral hepatitis Viremia Viremia - drug therapy Viremia - virology Virion Virion - drug effects Virion - ultrastructure Virus Replication - drug effects |
| title | Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly |
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