Bioluminescence imaging of metabolites in a human tumour xenograft after treatment with hyperthermia and/or the radiosensitizer pimonidazole

The levels and distribution of ATP, glucose and lactate in human tumour xenografts following either single or combined treatment with hyperthermia (43°C for 30 min) and/or pimonidazole (1mg/gb.w) were determined by bioluminescence and compared with the mean 'global' levels obtained from th...

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Veröffentlicht in:	International journal of hyperthermia 1997, Vol.13 (2), p.235-245
Hauptverfasser:	Tamulevicius, P., Streffer, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Biological and medical sciences Bioluminescence Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - therapy Combined Modality Therapy Glucose - metabolism Humans hyperthermia Hyperthermia, Induced Induced hyperthermia. Cryotherapy Lactic Acid - metabolism Luminescent Measurements Medical sciences Mice Mice, Nude Neoplasm Transplantation Neoplasms, Experimental - therapy Nitroimidazoles - therapeutic use Radiation-Sensitizing Agents - therapeutic use radiosensitizer Temperature Transplantation, Heterologous Treatment with physical agents Treatment. General aspects Tumors tumour metabolism
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