Ondansetron loaded pectin based microspheres for nasal administration: In vitro and in vivo studies

The aim of this study was the production of ondansetron hydrochloride loaded polymeric microspheres for delivery via the nasal route with aim to avoid hepatic first-pass metabolism, and enhance residence time. The microspheres were prepared by the spray–drying technique using pectin as the polymer....

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Veröffentlicht in:Powder technology 2012, Vol.221, p.168-176
Hauptverfasser: Mahajan, Hitendra S, Tatiya, Bhushankumar V, Nerkar, Pankaj P
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Sprache:eng
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