Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2011-02, Vol.55 (2), p.680-687 |
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creator | XIAOPING ZHANG FETTNER, Scott ZWANZIGER, Elke ROWELL, Lucy SALGO, Miklos |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00992-10</identifier><identifier>PMID: 21135186</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Adolescent ; Adult ; Aged ; Antibiotics, Antitubercular ; Antibiotics, Antitubercular - administration & dosage ; Antibiotics, Antitubercular - adverse effects ; Antibiotics, Antitubercular - pharmacokinetics ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Area Under Curve ; Biological and medical sciences ; Cross-Over Studies ; Drug Administration Schedule ; Drug Interactions ; Drug Therapy, Combination ; Female ; HIV Protease Inhibitors ; HIV Protease Inhibitors - administration & dosage ; HIV Protease Inhibitors - adverse effects ; HIV Protease Inhibitors - pharmacokinetics ; Humans ; Male ; Medical sciences ; Middle Aged ; Pharmacology ; Pharmacology. Drug treatments ; Rifabutin ; Rifabutin - administration & dosage ; Rifabutin - adverse effects ; Rifabutin - pharmacokinetics ; Ritonavir ; Ritonavir - administration & dosage ; Ritonavir - adverse effects ; Ritonavir - pharmacokinetics ; Saquinavir ; Saquinavir - administration & dosage ; Saquinavir - adverse effects ; Saquinavir - pharmacokinetics ; Young Adult</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2011-02, Vol.55 (2), p.680-687</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology</rights><rights>Copyright © 2011, American Society for Microbiology 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a504t-2f51350c52825fe4a9729a6e0a2ef94b24a5e660872de5e72d16e6fd16f59f93</citedby><cites>FETCH-LOGICAL-a504t-2f51350c52825fe4a9729a6e0a2ef94b24a5e660872de5e72d16e6fd16f59f93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028758/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028758/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23828809$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21135186$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>XIAOPING ZHANG</creatorcontrib><creatorcontrib>FETTNER, Scott</creatorcontrib><creatorcontrib>ZWANZIGER, Elke</creatorcontrib><creatorcontrib>ROWELL, Lucy</creatorcontrib><creatorcontrib>SALGO, Miklos</creatorcontrib><title>Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Antibiotics, Antitubercular</subject><subject>Antibiotics, Antitubercular - administration & dosage</subject><subject>Antibiotics, Antitubercular - adverse effects</subject><subject>Antibiotics, Antitubercular - pharmacokinetics</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Area Under Curve</subject><subject>Biological and medical sciences</subject><subject>Cross-Over Studies</subject><subject>Drug Administration Schedule</subject><subject>Drug Interactions</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>HIV Protease Inhibitors</subject><subject>HIV Protease Inhibitors - administration & dosage</subject><subject>HIV Protease Inhibitors - adverse effects</subject><subject>HIV Protease Inhibitors - pharmacokinetics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Rifabutin</subject><subject>Rifabutin - administration & dosage</subject><subject>Rifabutin - adverse effects</subject><subject>Rifabutin - pharmacokinetics</subject><subject>Ritonavir</subject><subject>Ritonavir - administration & dosage</subject><subject>Ritonavir - adverse effects</subject><subject>Ritonavir - pharmacokinetics</subject><subject>Saquinavir</subject><subject>Saquinavir - administration & dosage</subject><subject>Saquinavir - adverse effects</subject><subject>Saquinavir - pharmacokinetics</subject><subject>Young Adult</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kVFvFCEQx4nR2LP65rPZF2NM3ArswsFLk_NSbZMmGq_vZJaDLucutMC2uW9fendWfTAhQ2bmN_-BGYTeEnxCCBWfF4vlCcZS0prgZ2hGsBQ1Z5I_RzOMOa9bgdsj9CqlDS4-k_glOqKENIwIPkPpRw9xBB1-OW-y09WFzyaCzi74apWn9bYKtvrpcvBw52L9JYSUzbpawe3kdqHK-WoZxq54u6J7l_tSYKGbckmVc25gyP22Wk3dxuicXqMXFoZk3hzuY3T19exqeV5ffv92sVxc1sBwm2tqWXkl1owKyqxpQc6pBG4wUGNl29EWmOEcizldG2aKJdxwW6xl0srmGJ3uZW-mbjRrbXyOMKib6EaIWxXAqX8z3vXqOtypBlMxZ6IIfDgIxHA7mZTV6JI2wwDehCkpieeklYTwQn7akzqGlKKxT10IVo9bUmVLarelEin4xz0OaaRqE6boyxz-x777-xdPwr9XWID3BwCShsFG8NqlP1wjqBD4cRzVnuvddX_volGluwLQijFFFRe4eQDV_7P_</recordid><startdate>20110201</startdate><enddate>20110201</enddate><creator>XIAOPING ZHANG</creator><creator>FETTNER, Scott</creator><creator>ZWANZIGER, Elke</creator><creator>ROWELL, Lucy</creator><creator>SALGO, Miklos</creator><general>American Society for Microbiology</general><general>American Society for Microbiology (ASM)</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>20110201</creationdate><title>Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects</title><author>XIAOPING ZHANG ; FETTNER, Scott ; ZWANZIGER, Elke ; ROWELL, Lucy ; SALGO, Miklos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a504t-2f51350c52825fe4a9729a6e0a2ef94b24a5e660872de5e72d16e6fd16f59f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Antibiotics, Antitubercular</topic><topic>Antibiotics, Antitubercular - administration & dosage</topic><topic>Antibiotics, Antitubercular - adverse effects</topic><topic>Antibiotics, Antitubercular - pharmacokinetics</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Area Under Curve</topic><topic>Biological and medical sciences</topic><topic>Cross-Over Studies</topic><topic>Drug Administration Schedule</topic><topic>Drug Interactions</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>HIV Protease Inhibitors</topic><topic>HIV Protease Inhibitors - administration & dosage</topic><topic>HIV Protease Inhibitors - adverse effects</topic><topic>HIV Protease Inhibitors - pharmacokinetics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Rifabutin</topic><topic>Rifabutin - administration & dosage</topic><topic>Rifabutin - adverse effects</topic><topic>Rifabutin - pharmacokinetics</topic><topic>Ritonavir</topic><topic>Ritonavir - administration & dosage</topic><topic>Ritonavir - adverse effects</topic><topic>Ritonavir - pharmacokinetics</topic><topic>Saquinavir</topic><topic>Saquinavir - administration & dosage</topic><topic>Saquinavir - adverse effects</topic><topic>Saquinavir - pharmacokinetics</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>XIAOPING ZHANG</creatorcontrib><creatorcontrib>FETTNER, Scott</creatorcontrib><creatorcontrib>ZWANZIGER, Elke</creatorcontrib><creatorcontrib>ROWELL, Lucy</creatorcontrib><creatorcontrib>SALGO, Miklos</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>XIAOPING ZHANG</au><au>FETTNER, Scott</au><au>ZWANZIGER, Elke</au><au>ROWELL, Lucy</au><au>SALGO, Miklos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2011-02-01</date><risdate>2011</risdate><volume>55</volume><issue>2</issue><spage>680</spage><epage>687</epage><pages>680-687</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21135186</pmid><doi>10.1128/AAC.00992-10</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Adolescent Adult Aged Antibiotics, Antitubercular Antibiotics, Antitubercular - administration & dosage Antibiotics, Antitubercular - adverse effects Antibiotics, Antitubercular - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Area Under Curve Biological and medical sciences Cross-Over Studies Drug Administration Schedule Drug Interactions Drug Therapy, Combination Female HIV Protease Inhibitors HIV Protease Inhibitors - administration & dosage HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - pharmacokinetics Humans Male Medical sciences Middle Aged Pharmacology Pharmacology. Drug treatments Rifabutin Rifabutin - administration & dosage Rifabutin - adverse effects Rifabutin - pharmacokinetics Ritonavir Ritonavir - administration & dosage Ritonavir - adverse effects Ritonavir - pharmacokinetics Saquinavir Saquinavir - administration & dosage Saquinavir - adverse effects Saquinavir - pharmacokinetics Young Adult |
title | Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects |
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