Multiple-Layer Compression-Coated Tablets: Formulation and Humidity Studies of Novel Chewable Amoxicillin/Clavulanate Tablet Formulations

Abstract The purpose of this study was to produce novel multiple-layer, compression-coated, chewable tablet formulations containing amoxicillin trihydrate, and clavulanic acid as potassium clavulanate, and to test in vitro dissolution characteristics and the effect of humidity stability compared to...

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Veröffentlicht in:	Drug development and industrial pharmacy 1998-01, Vol.24 (8), p.729-736
Hauptverfasser:	Wardrop, Jacqueline, Jaber, Ahmad Bani, Ayres, James W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amoxicillin - administration & dosage Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Clavulanic Acid - administration & dosage Drug Stability Drug Therapy, Combination - administration & dosage General pharmacology Humidity Mastication Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Solubility Tablets, Enteric-Coated
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