Sustained release theophylline tablets by direct compression: Part 1: formulation and in vitro testing

In an effort to reduce production costs, a simple, direct compression sustained release formulation consisting, principally, of the drug (theophylline) and ethylcellulose was investigated. Ethylcellulose compacts well and also retards drug release. In addition, matrices of this polymer display slow...

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Veröffentlicht in:	International journal of pharmaceutics 1998-04, Vol.164 (1), p.1-10
Hauptverfasser:	Pather, S.Indiran, Russell, Irina, Syce, James A, Neau, Steven H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Erosion Ethylcellulose General pharmacology Mathematical modeling Matrix tablets Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymeric retardants Respiratory system Sustained release Theophylline
Online-Zugang:	Volltext
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