A randomized clinical trial of exercise to alleviate postpartum depressed mood

Objective. To evaluate whether a 12-week home-based exercise program is more effective than usual care for alleviating depressive symptomology in the postpartum. Methods. Eighty-eight women experiencing postpartum depressed mood were randomly assigned to a 12-week home-based exercise program or usua...

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Veröffentlicht in:Journal of psychosomatic obstetrics and gynaecology 2009-01, Vol.30 (3), p.191-200
Hauptverfasser: Da Costa, Deborah, Lowensteyn, Ilka, Abrahamowicz, Michal, Ionescu-Ittu, Raluca, Dritsa, Maria, Rippen, Natalie, Cervantes, Pablo, Khalifé, Samir
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container_end_page 200
container_issue 3
container_start_page 191
container_title Journal of psychosomatic obstetrics and gynaecology
container_volume 30
creator Da Costa, Deborah
Lowensteyn, Ilka
Abrahamowicz, Michal
Ionescu-Ittu, Raluca
Dritsa, Maria
Rippen, Natalie
Cervantes, Pablo
Khalifé, Samir
description Objective. To evaluate whether a 12-week home-based exercise program is more effective than usual care for alleviating depressive symptomology in the postpartum. Methods. Eighty-eight women experiencing postpartum depressed mood were randomly assigned to a 12-week home-based exercise program or usual care. Outcomes assessed immediately post-treatment and 3-months post-treatment were the Hamilton Rating Scale for Depression (HAM-D) and Edinburgh Postnatal Depression Scale (EPDS). Results. In the intention-to-treat analysis, the effect of the intervention on EPDS did not change from 3 to 6 months evaluations, but was modified by the baseline EPDS score, with subjects with greater depression at baseline (EPDS > 13) in the intervention group having a significantly lower postbaseline EPDS score compared with the usual care group (mean difference 4.06 points, 95%CI 1.51-6.61, p < 0.001). After adjusting for baseline HAM-D, subjects in the intervention group had a significantly lower HAM-D score at post-treatment compared with subjects in the usual care group (mean difference 1.83 points, 95%CI 0.24-3.41, p = 0.02). The difference in HAM-D became non-significant at 3-months post-treatment. Conclusions. Home-based exercise is a feasible nonpharmacological intervention with the potential to alleviate postpartum depressive symptoms, especially in women with higher initial depressed mood scores as measured by the EPDS. These findings may guide the design of future exercise clinical trials with postpartum depressed women.
doi_str_mv 10.1080/01674820903212136
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To evaluate whether a 12-week home-based exercise program is more effective than usual care for alleviating depressive symptomology in the postpartum. Methods. Eighty-eight women experiencing postpartum depressed mood were randomly assigned to a 12-week home-based exercise program or usual care. Outcomes assessed immediately post-treatment and 3-months post-treatment were the Hamilton Rating Scale for Depression (HAM-D) and Edinburgh Postnatal Depression Scale (EPDS). Results. In the intention-to-treat analysis, the effect of the intervention on EPDS did not change from 3 to 6 months evaluations, but was modified by the baseline EPDS score, with subjects with greater depression at baseline (EPDS &gt; 13) in the intervention group having a significantly lower postbaseline EPDS score compared with the usual care group (mean difference 4.06 points, 95%CI 1.51-6.61, p &lt; 0.001). After adjusting for baseline HAM-D, subjects in the intervention group had a significantly lower HAM-D score at post-treatment compared with subjects in the usual care group (mean difference 1.83 points, 95%CI 0.24-3.41, p = 0.02). The difference in HAM-D became non-significant at 3-months post-treatment. Conclusions. Home-based exercise is a feasible nonpharmacological intervention with the potential to alleviate postpartum depressive symptoms, especially in women with higher initial depressed mood scores as measured by the EPDS. These findings may guide the design of future exercise clinical trials with postpartum depressed women.</description><identifier>ISSN: 0167-482X</identifier><identifier>EISSN: 1743-8942</identifier><identifier>DOI: 10.1080/01674820903212136</identifier><identifier>PMID: 19728220</identifier><identifier>CODEN: JPOGDP</identifier><language>eng</language><publisher>New York, NY: Informa UK Ltd</publisher><subject>Adult ; Adult and adolescent clinical studies ; Biological and medical sciences ; Depression ; Depression, Postpartum - diagnosis ; Depression, Postpartum - psychology ; Depression, Postpartum - therapy ; Exercise - psychology ; Feasibility Studies ; Female ; home-based exercise ; Humans ; Medical sciences ; Miscellaneous ; Mood disorders ; Personality Inventory ; Physical Fitness - psychology ; Postpartum depressed mood ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. 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To evaluate whether a 12-week home-based exercise program is more effective than usual care for alleviating depressive symptomology in the postpartum. Methods. Eighty-eight women experiencing postpartum depressed mood were randomly assigned to a 12-week home-based exercise program or usual care. Outcomes assessed immediately post-treatment and 3-months post-treatment were the Hamilton Rating Scale for Depression (HAM-D) and Edinburgh Postnatal Depression Scale (EPDS). Results. In the intention-to-treat analysis, the effect of the intervention on EPDS did not change from 3 to 6 months evaluations, but was modified by the baseline EPDS score, with subjects with greater depression at baseline (EPDS &gt; 13) in the intervention group having a significantly lower postbaseline EPDS score compared with the usual care group (mean difference 4.06 points, 95%CI 1.51-6.61, p &lt; 0.001). After adjusting for baseline HAM-D, subjects in the intervention group had a significantly lower HAM-D score at post-treatment compared with subjects in the usual care group (mean difference 1.83 points, 95%CI 0.24-3.41, p = 0.02). The difference in HAM-D became non-significant at 3-months post-treatment. Conclusions. Home-based exercise is a feasible nonpharmacological intervention with the potential to alleviate postpartum depressive symptoms, especially in women with higher initial depressed mood scores as measured by the EPDS. These findings may guide the design of future exercise clinical trials with postpartum depressed women.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Depression</subject><subject>Depression, Postpartum - diagnosis</subject><subject>Depression, Postpartum - psychology</subject><subject>Depression, Postpartum - therapy</subject><subject>Exercise - psychology</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>home-based exercise</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Mood disorders</subject><subject>Personality Inventory</subject><subject>Physical Fitness - psychology</subject><subject>Postpartum depressed mood</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Quebec</subject><subject>randomized controlled trial</subject><subject>Treatment Outcome</subject><subject>Treatments</subject><issn>0167-482X</issn><issn>1743-8942</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtO3DAUQK2KqgzQD2CDsqG7tH4kTqx2M0IFKqGyAam76I5zLYycONgOr6_Ho5kWoUps7IXPufI9hBwy-pXRln6jTDZVy6migjPOhPxAFqypRNmqiu-Qxfq9zMCfXbIX4y2lXGToE9llquEt53RBfi-LAGPvB_uMfaGdHa0GV6Rg8-lNgY8YtI1YJF-Ac3hvIWEx-ZgmCGkeih6ngDFmefC-PyAfDbiIn7f3Prk-_Xl1cl5eXJ79OllelLoSVSoVF6tec2OEalul0chKcJQSG10LWLXUVA1IZkBRzWsOKLmUje7Vqq6UNkrsky-buVPwdzPG1A02anQORvRz7GQjhaB0DbINqIOPMaDppmAHCE8do906YvdfxOwcbYfPqwH7V2NbLQPHWwBirmVywdzoH8eZamUt68z92HB2ND4M8OCD67sET86Hv5J47x_f3-g3CC7daAjY3fo5jDnwO1u8AL_unxY</recordid><startdate>20090101</startdate><enddate>20090101</enddate><creator>Da Costa, Deborah</creator><creator>Lowensteyn, Ilka</creator><creator>Abrahamowicz, Michal</creator><creator>Ionescu-Ittu, Raluca</creator><creator>Dritsa, Maria</creator><creator>Rippen, Natalie</creator><creator>Cervantes, Pablo</creator><creator>Khalifé, Samir</creator><general>Informa UK Ltd</general><general>Taylor &amp; Francis</general><general>Informa Healthcare</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090101</creationdate><title>A randomized clinical trial of exercise to alleviate postpartum depressed mood</title><author>Da Costa, Deborah ; Lowensteyn, Ilka ; Abrahamowicz, Michal ; Ionescu-Ittu, Raluca ; Dritsa, Maria ; Rippen, Natalie ; Cervantes, Pablo ; Khalifé, Samir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-923bdc2ff39889cef6432e66e7c53ab80f47a61fa90c252ae62667cd9b549cf93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Depression</topic><topic>Depression, Postpartum - diagnosis</topic><topic>Depression, Postpartum - psychology</topic><topic>Depression, Postpartum - therapy</topic><topic>Exercise - psychology</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>home-based exercise</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Personality Inventory</topic><topic>Physical Fitness - psychology</topic><topic>Postpartum depressed mood</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Quebec</topic><topic>randomized controlled trial</topic><topic>Treatment Outcome</topic><topic>Treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Da Costa, Deborah</creatorcontrib><creatorcontrib>Lowensteyn, Ilka</creatorcontrib><creatorcontrib>Abrahamowicz, Michal</creatorcontrib><creatorcontrib>Ionescu-Ittu, Raluca</creatorcontrib><creatorcontrib>Dritsa, Maria</creatorcontrib><creatorcontrib>Rippen, Natalie</creatorcontrib><creatorcontrib>Cervantes, Pablo</creatorcontrib><creatorcontrib>Khalifé, Samir</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychosomatic obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Da Costa, Deborah</au><au>Lowensteyn, Ilka</au><au>Abrahamowicz, Michal</au><au>Ionescu-Ittu, Raluca</au><au>Dritsa, Maria</au><au>Rippen, Natalie</au><au>Cervantes, Pablo</au><au>Khalifé, Samir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A randomized clinical trial of exercise to alleviate postpartum depressed mood</atitle><jtitle>Journal of psychosomatic obstetrics and gynaecology</jtitle><addtitle>J Psychosom Obstet Gynaecol</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>30</volume><issue>3</issue><spage>191</spage><epage>200</epage><pages>191-200</pages><issn>0167-482X</issn><eissn>1743-8942</eissn><coden>JPOGDP</coden><abstract>Objective. To evaluate whether a 12-week home-based exercise program is more effective than usual care for alleviating depressive symptomology in the postpartum. Methods. Eighty-eight women experiencing postpartum depressed mood were randomly assigned to a 12-week home-based exercise program or usual care. Outcomes assessed immediately post-treatment and 3-months post-treatment were the Hamilton Rating Scale for Depression (HAM-D) and Edinburgh Postnatal Depression Scale (EPDS). Results. In the intention-to-treat analysis, the effect of the intervention on EPDS did not change from 3 to 6 months evaluations, but was modified by the baseline EPDS score, with subjects with greater depression at baseline (EPDS &gt; 13) in the intervention group having a significantly lower postbaseline EPDS score compared with the usual care group (mean difference 4.06 points, 95%CI 1.51-6.61, p &lt; 0.001). After adjusting for baseline HAM-D, subjects in the intervention group had a significantly lower HAM-D score at post-treatment compared with subjects in the usual care group (mean difference 1.83 points, 95%CI 0.24-3.41, p = 0.02). The difference in HAM-D became non-significant at 3-months post-treatment. Conclusions. Home-based exercise is a feasible nonpharmacological intervention with the potential to alleviate postpartum depressive symptoms, especially in women with higher initial depressed mood scores as measured by the EPDS. These findings may guide the design of future exercise clinical trials with postpartum depressed women.</abstract><cop>New York, NY</cop><pub>Informa UK Ltd</pub><pmid>19728220</pmid><doi>10.1080/01674820903212136</doi><tpages>10</tpages></addata></record>
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1743-8942
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subjects Adult
Adult and adolescent clinical studies
Biological and medical sciences
Depression
Depression, Postpartum - diagnosis
Depression, Postpartum - psychology
Depression, Postpartum - therapy
Exercise - psychology
Feasibility Studies
Female
home-based exercise
Humans
Medical sciences
Miscellaneous
Mood disorders
Personality Inventory
Physical Fitness - psychology
Postpartum depressed mood
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Quebec
randomized controlled trial
Treatment Outcome
Treatments
title A randomized clinical trial of exercise to alleviate postpartum depressed mood
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