Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

Recent advances in immunology have highlighted the critical function of pattern-recognition molecules (PRMs) in generating the innate immune response to effectively target pathogens. Nod1 and Nod2 are intracellular PRMs that detect peptidoglycan motifs from the cell walls of bacteria once they gain...

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Veröffentlicht in:	Infection and Immunity 2009-10, Vol.77 (10), p.4480-4486
Hauptverfasser:	Le Bourhis, Lionel, Magalhaes, Joao Gamelas, Selvanantham, Thirumahal, Travassos, Leonardo H, Geddes, Kaoru, Fritz, Jörg H, Viala, Jérôme, Tedin, Karsten, Girardin, Stephen E, Philpott, Dana J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Bacterial diseases Bacterial diseases of the digestive system and abdomen Bacteriology Biological and medical sciences Bone marrow Cell survival Cell walls Chimeras Colonization Colony Count, Microbial Cytosol Dendritic cells Dendritic Cells - immunology Dendritic Cells - microbiology Fundamental and applied biological sciences. Psychology Gene Deletion Host Response and Inflammation Human bacterial diseases Infectious diseases Intestine lamina propria Liver - microbiology Lymph Nodes - microbiology Medical sciences Mice Mice, Inbred C57BL Microbiology Miscellaneous Mucosa Myeloid cells Nod1 protein Nod1 Signaling Adaptor Protein - deficiency Nod1 Signaling Adaptor Protein - immunology NOD2 protein Nod2 Signaling Adaptor Protein - deficiency Nod2 Signaling Adaptor Protein - immunology Oral infection pathogenicity islands Pathogens peptidoglycans Salmonella enterica Salmonella Infections - immunology Salmonella Infections - microbiology Salmonella typhimurium Salmonella typhimurium - growth & development Salmonella typhimurium - immunology Spleen - microbiology Survival Analysis Vacuoles
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