Preventive Effects of Heregulin-β1 on Macrophage Foam Cell Formation and Atherosclerosis

RATIONALE:Human heregulins, neuregulin-1 type I polypeptides that activate proliferation, differentiation, and survival of glial cells, neurons, and myocytes, are expressed in macrophage foam cells within human coronary atherosclerotic lesions. Macrophage foam cell formation, characterized by choles...

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Veröffentlicht in:	Circulation research 2009-08, Vol.105 (5), p.500-510
Hauptverfasser:	Xu, Gang, Watanabe, Takuya, Iso, Yoshitaka, Koba, Shinji, Sakai, Tetsuo, Nagashima, Masaharu, Arita, Shigeko, Hongo, Shigeki, Ota, Hidekazu, Kobayashi, Youichi, Miyazaki, Akira, Hirano, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Coronary heart disease Fundamental and applied biological sciences. Psychology Heart Medical sciences Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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