Bone Penetration of Amoxicillin and Clavulanic Acid Evaluated by Population Pharmacokinetics and Monte Carlo Simulation
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2009-06, Vol.53 (6), p.2569-2578 |
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creator | Landersdorfer, Cornelia B Kinzig, Martina Bulitta, Jürgen B Hennig, Friedrich F Holzgrabe, Ulrike Sörgel, Fritz Gusinde, Johannes |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.01119-08</identifier><identifier>PMID: 19307356</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Adult ; Aged ; Amoxicillin ; Amoxicillin - pharmacokinetics ; Amoxicillin - pharmacology ; Anti-Bacterial Agents ; Anti-Bacterial Agents - pharmacokinetics ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Area Under Curve ; Biological and medical sciences ; Bone and Bones ; Bone and Bones - metabolism ; Clavulanic Acid ; Clavulanic Acid - pharmacokinetics ; Clavulanic Acid - pharmacology ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Monte Carlo Method ; Osteomyelitis - drug therapy ; Pharmacology ; Pharmacology. Drug treatments ; Staphylococcus aureus</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2009-06, Vol.53 (6), p.2569-2578</ispartof><rights>2009 INIST-CNRS</rights><rights>Copyright © 2009 American Society for Microbiology</rights><rights>Copyright © 2009, American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a569t-1a345b3d73526d471c42855647fa40d5c8b09f5ee3dfab6667be377a04c521b73</citedby><cites>FETCH-LOGICAL-a569t-1a345b3d73526d471c42855647fa40d5c8b09f5ee3dfab6667be377a04c521b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687224/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687224/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21538687$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19307356$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Landersdorfer, Cornelia B</creatorcontrib><creatorcontrib>Kinzig, Martina</creatorcontrib><creatorcontrib>Bulitta, Jürgen B</creatorcontrib><creatorcontrib>Hennig, Friedrich F</creatorcontrib><creatorcontrib>Holzgrabe, Ulrike</creatorcontrib><creatorcontrib>Sörgel, Fritz</creatorcontrib><creatorcontrib>Gusinde, Johannes</creatorcontrib><title>Bone Penetration of Amoxicillin and Clavulanic Acid Evaluated by Population Pharmacokinetics and Monte Carlo Simulation</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Adult</subject><subject>Aged</subject><subject>Amoxicillin</subject><subject>Amoxicillin - pharmacokinetics</subject><subject>Amoxicillin - pharmacology</subject><subject>Anti-Bacterial Agents</subject><subject>Anti-Bacterial Agents - pharmacokinetics</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Area Under Curve</subject><subject>Biological and medical sciences</subject><subject>Bone and Bones</subject><subject>Bone and Bones - metabolism</subject><subject>Clavulanic Acid</subject><subject>Clavulanic Acid - pharmacokinetics</subject><subject>Clavulanic Acid - pharmacology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Monte Carlo Method</subject><subject>Osteomyelitis - drug therapy</subject><subject>Pharmacology</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Area Under Curve</topic><topic>Biological and medical sciences</topic><topic>Bone and Bones</topic><topic>Bone and Bones - metabolism</topic><topic>Clavulanic Acid</topic><topic>Clavulanic Acid - pharmacokinetics</topic><topic>Clavulanic Acid - pharmacology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Monte Carlo Method</topic><topic>Osteomyelitis - drug therapy</topic><topic>Pharmacology</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>19307356</pmid><doi>10.1128/aac.01119-08</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Adult Aged Amoxicillin Amoxicillin - pharmacokinetics Amoxicillin - pharmacology Anti-Bacterial Agents Anti-Bacterial Agents - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Area Under Curve Biological and medical sciences Bone and Bones Bone and Bones - metabolism Clavulanic Acid Clavulanic Acid - pharmacokinetics Clavulanic Acid - pharmacology Female Humans Male Medical sciences Middle Aged Monte Carlo Method Osteomyelitis - drug therapy Pharmacology Pharmacology. Drug treatments Staphylococcus aureus |
title | Bone Penetration of Amoxicillin and Clavulanic Acid Evaluated by Population Pharmacokinetics and Monte Carlo Simulation |
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