Improved local delivery of TGF-β2 by binding to injectable fibrillar collagen via difunctional polyethylene glycol

To overcome rapid diffusion and clearance from the implant site and to increase stability, recombinant transforming growth factor β2 (TGF‐β2) was covalently bound to injectable bovine dermal fibrillar collagen (FC) and its activity compared to admixed TGF‐β2. Covalent binding was achieved in a two‐s...

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Veröffentlicht in:	Journal of biomedical materials research 1998-03, Vol.39 (4), p.539-548
Hauptverfasser:	Bentz, H., Schroeder, J. A., Estridge, T. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences biomaterials collagen cytokine delivery via covalent binding Medical sciences polyethylene glycol Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments tissue repair transforming growth factor β
Online-Zugang:	Volltext
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