A Convenient, One-Step Synthesis of Benzyl (Ar) Ureas of the Type ArCH2NHCONHR from Ar and R1OCH2NHCONHR via Ureidoalkylation

A method for the one-step C-ureidoalkylation of phenol, anisole, or aniline rings furnishing ArCH2NHCONHR (Ar = benzyl) products in moderate to good yields is described. With phenol ring systems, higher yields were attained when the reaction was worked up with an acidic ethanethiol addition to cleav...

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Veröffentlicht in:	Journal of organic chemistry 2009-04, Vol.74 (8), p.3156-3159
Hauptverfasser:	Meece, F. Alex, Jayasinghe, Champika, Histand, Gary, Burns, Dennis H
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Noncondensed benzenic compounds Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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